Skip to main content

Table 1 Baseline characteristics of patients choosing dialysis or conservative care, determined at treatment decision

From: Value-based evaluation of dialysis versus conservative care in older patients with advanced chronic kidney disease: a cohort study

  Dialysis (n = 240) Conservative care (n = 126) P value
Age (years), mean (SD) 76.2 (4.4) 82.6 (4.5) <  0.001
Aged ≥80 years 55 (23%) 93 (74%) <  0.001
Sex (female) 80 (33%) 58 (46%) 0.02
Davies comorbidity score 0.73
 No comorbidity (score = 0) 27 (11%) 11 (9%)  
 Intermediate comorbidity (score = 1 or 2) 142 (59%) 75 (59%)  
 Severe comorbidity (score ≥ 3) 71 (30%) 40 (32%)  
Primary renal diagnoses 0.12
 Renal vascular disease 82 (34%) 58 (46%)  
 Diabetes mellitus 40 (17%) 16 (13%)  
 Hypertension 21 (9%) 7 (6%)  
 Pyelonephritis 5 (2%) 5 (4%)  
 Polycystic kidneys 7 (3%) 1 (1%)  
 Glomerulonephritis 7 (3%) 0 (0%)  
 Cause unknown 58 (24%) 30 (24%)  
 Other 20 (8%) 9 (7%)  
Body mass index (kg/m2), mean (SD) 27.0 (4.5; n = 196) 26.2 (4.8; n = 98) 0.16
Albumin (g/l), mean (SD) 39.2 (4.6; n = 186) 38.8 (3.5; n = 109) 0.42
C-reactive protein (nmol/l), median (IQR) 47.6 (28.6–95.2; n = 173) 47.6 (28.6–123.8; n = 93) 0.12
eGFR at treatment decision (mL/min/1.73m2), mean (SD) 13.3 (4.3) 15.6 (5.0) <  0.001
Time of eGFR decline from < 20 to < 15 mL/min/1.73m2(days), median (IQR) 238 (52–461; n = 188) 212 (0–564; n = 80) 0.55
Time from treatment decision to dialysis initiation (days), median (IQR) 146 (48–437; n = 146)   
eGFR at start of dialysis (mL/min/1.73m2), mean (SD) 8.4 (2.9; n = 146)   
  1. Values are numbers (percentages) unless stated otherwise
  2. eGFR estimated glomerular filtration rate, IQR interquartile range, SD standard deviation