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Table 1 Baseline characteristics of patients choosing dialysis or conservative care, determined at treatment decision

From: Value-based evaluation of dialysis versus conservative care in older patients with advanced chronic kidney disease: a cohort study

 

Dialysis (n = 240)

Conservative care (n = 126)

P value

Age (years), mean (SD)

76.2 (4.4)

82.6 (4.5)

<  0.001

Aged ≥80 years

55 (23%)

93 (74%)

<  0.001

Sex (female)

80 (33%)

58 (46%)

0.02

Davies comorbidity score

0.73

 No comorbidity (score = 0)

27 (11%)

11 (9%)

 

 Intermediate comorbidity (score = 1 or 2)

142 (59%)

75 (59%)

 

 Severe comorbidity (score ≥ 3)

71 (30%)

40 (32%)

 

Primary renal diagnoses

0.12

 Renal vascular disease

82 (34%)

58 (46%)

 

 Diabetes mellitus

40 (17%)

16 (13%)

 

 Hypertension

21 (9%)

7 (6%)

 

 Pyelonephritis

5 (2%)

5 (4%)

 

 Polycystic kidneys

7 (3%)

1 (1%)

 

 Glomerulonephritis

7 (3%)

0 (0%)

 

 Cause unknown

58 (24%)

30 (24%)

 

 Other

20 (8%)

9 (7%)

 

Body mass index (kg/m2), mean (SD)

27.0 (4.5; n = 196)

26.2 (4.8; n = 98)

0.16

Albumin (g/l), mean (SD)

39.2 (4.6; n = 186)

38.8 (3.5; n = 109)

0.42

C-reactive protein (nmol/l), median (IQR)

47.6 (28.6–95.2; n = 173)

47.6 (28.6–123.8; n = 93)

0.12

eGFR at treatment decision (mL/min/1.73m2), mean (SD)

13.3 (4.3)

15.6 (5.0)

<  0.001

Time of eGFR decline from < 20 to < 15 mL/min/1.73m2(days), median (IQR)

238 (52–461; n = 188)

212 (0–564; n = 80)

0.55

Time from treatment decision to dialysis initiation (days), median (IQR)

146 (48–437; n = 146)

  

eGFR at start of dialysis (mL/min/1.73m2), mean (SD)

8.4 (2.9; n = 146)

  
  1. Values are numbers (percentages) unless stated otherwise
  2. eGFR estimated glomerular filtration rate, IQR interquartile range, SD standard deviation