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Table 2 Baseline Characteristics according to Monthly Income Level

From: The association between socioeconomic disparities and left ventricular hypertrophy in chronic kidney disease: results from the KoreaN Cohort Study for Outcomes in Patients With Chronic Kidney Disease (KNOW-CKD)

N

Total

Monthly income

P

P for trend

> $ 4500

$1500 to $4500

< $ 1500

1361

269

701

391

Age (year, mean ± SD)

60.9 ± 6.9

59.0 ± 6.6

60.6 ± 6.9

62.8 ± 6.7

< 0.001

< 0.001

Male (N, %)

860 (63.2)

199 (74.0)

433 (61.8)

228 (58.3)

< 0.001

< 0.001

LVH (N, %)

413 (30.3)

60 (22.3)

205 (29.2)

148 (37.9)

< 0.001

< 0.001

eGFR (mL/min/1.73m2)

45.5 ± 25.1

49.9 ± 24.9

46.5 ± 25.2

40.5 ± 24.3

< 0.001

< 0.001

BMI (kg/m2, mean ± SD)

24.6 ± 3.1

24.6 ± 2.8

24.6 ± 3.2

24.7 ± 3.2

0.586

0.403

CKD stage (N, %)

    

< 0.001

< 0.001

 Stage G1

112 (8.2)

27 (10.0)

60 (8.6)

25 (6.4)

  

 Stage G2

226 (16.6)

58 (21.6)

115 (16.4)

53 (13.6)

  

 Stage G3a

250 (18.4)

54 (20.1)

145 (20.7)

51 (13.0)

  

 Stage G3b

322 (23.7)

60 (22.3)

171 (24.4)

91 (23.3)

  

 Stage G4

352 (25.9)

59 (21.9)

162 (23.1)

131 (33.5)

  

 Stage G5

99 (7.3)

11 (4.1)

48 (6.8)

40 (10.2)

  

Underlying renal disease (N, %)

    

< 0.001

< 0.001

 Diabetic nephropathy

429 (31.8)

59 (22.0)

223 (32.2)

147 (27.8)

  

 Hypertensive nephropathy

327 (24.2)

71 (25.4)

173 (25.0)

83 (21.3)

  

 Glomerulonephritis

341 (25.3)

88 (32.8)

179 (25.8)

74 (19.0)

  

 Polycystic kidney disease

140 (10.4)

39 (14.6)

63 (9.1)

38 (9.8)

  

Diabetes mellitus (N, %)

571 (42.0)

88 (32.7)

291 (41.5)

192 (49.1)

  

bHemoglobin A1c (%, mean ± SD)

6.9 ± 1.4

6.8 ± 1.2

6.9 ± 1.3

7.0 ± 1.5

0.293

0.125

Hypertension (N, %)

1334 (98.0)

268 (99.6)

688 (98.1)

378 (96.7)

0.069

0.041

 Systolic blood pressure (mmHg)

128.84 ± 16.7

127.0 ± 14.1

128.3 ± 17.3

131.0 ± 17.1

0.005a

0.001

 Diastolic blood pressure (mmHg)

75.9 ± 11.2

77.1 ± 10.2

75.6 ± 11.3

75.8 ± 11.5

0.175

0.224

Educational attainment (N, %)

    

< 0.001

< 0.001

 College graduate or higher

437 (32.1)

163 (60.6)

214 (30.5)

60 (15.3)

  

 Completed high school

467 (34.3)

73 (27.1)

279 (39.8)

115 (29.4)

  

 Lower than high school

347 (33.6)

33 (12.3)

208 (29.7)

216 (55.2)

  

Physical activity (N, %)

    

< 0.001

< 0.001

 High

287 (21.1)

55 (20.4)

156 (22.3)

76 (19.4)

  

 Moderate

536 (39.4)

137 (50.9)

259 (36.9)

140 (35.8)

  

 Low

538 (39.5)

77 (28.6)

286 (40.8)

175 (44.8)

  

Anemia (N, %)

662 (49.1)

101 (37.8)

345 (49.8)

216 (55.8)

< 0.001

< 0.001

ESA (N, %)

119 (8.7)

12 (4.5)

71 (10.1)

36 (9.2)

0.019

0.01

Serum laboratory values

 Hemoglobin (g/dL)

12.6 ± 2.0

13.2 ± 1.9

12.6 ± 2.0

12.2 ± 1.9

< 0.001

< 0.001

 Creatinine (mg/dL)

1.9 ± 1.1

1.8 ± 1.0

1.9 ± 1.1

2.1 ± 1.2

< 0.001a

< 0.001

 Albumin (g/dL)

4.2 ± 0.4

4.2 ± 0.3

4.1 ± 0.4

4.1 ± 0.4

0.003a

0.001

 Calcium (mg/dL)

9.1 ± 0.5

9.2 ± 0.5

9.1 ± 0.5

9.1 ± 0.5

0.012

0.004

 Phosphorus (mg/dL)

3.7 ± 0.7

3.6 ± 0.5

3.7 ± 0.7

3.8 ± 0.7

0.003a

0.001

 Total cholesterol (mg/dL)

170.7 ± 38.2

171.0 ± 37.0

171.4 ± 39.4

159.3 ± 36.8

0.692a

0.508

 LDL (mg/dL)

93.1 ± 31.8

91.1 ± 32.4

94.4 ± 31.9

92.1 ± 31.1

0.281

0.851

 cHDL (mg/dL)

47.7 ± 14.6

49.7 ± 14.5

47.4 ± 14.2

46.9 ± 14.3

0.051

0.029

 dTriglyceride (mg/dL)

159.2 ± 95.7

143.7 ± 101.3

160.6 ± 100.0

159.6 ± 83.4

0.692

0.585

 e25-OH vitamin D (ng/mL)

18.5 ± 8.5

19.4 ± 8.2

18.7 ± 9.0

17.6 ± 7.9

0.019

0.006

f24 hour urine sodium (mmol/day)

154.8 ± 67.7

157.4 ± 67.5

152.1 ± 66.5

157.8 ± 69.6

0.348

0.797

  1. Abbreviations: SD standard deviation, eGFR estimated glomerular filtration rate, BMI body mass index, CKD chronic kidney disease, ESA erythropoiesis-stimulating agent, LDL low density lipoprotein, HDL high density lipoprotein
  2. aKruskal-Wallis test was used to evaluate P value
  3. bHemoglobin A1c was measured only in the diabetic patients. (Total 724 patients; >$4500, 115 patients; $1500 to $4500, 152 patients; <$1500, 252 patients)
  4. cHDL was measured in 1342 patients (missing value = 19)
  5. dTriglyceride was measured in 1329 patients (missing value = 32)
  6. e25-OH vitamin D was measured in 1331 patients (missing value = 30)
  7. f24 hour urine sodium was measured in 1240 patients (missing value = 121)