Clinical impact of endocapillary proliferation according to the Oxford classification among adults with Henoch-Schönlein purpura nephritis: a multicenter retrospective cohort study

Table 3 Comparison of clinical features according to three pathological classifications in 74 adults with HSPN

Factor	Age (years)	P values	eGFR (mL/min/1.73m²)	P values	Proteinuria (g/day)	P values
E0	47.4 ± 18.0	0.85	77.1 ± 29.2	0.83	0.77 [0.48–1.32]	< 0.001
E1	48.2 ± 17.0		75.7 ± 22.4		1.83 [1.40–4.58]
S0	46.9 ± 18.1	0.65	77.2 ± 26.6	0.80	1.38 [0.78–2.44]	0.74
S1	48.7 ± 16.8		75.6 ± 25.4		1.41 [0.64–2.25]
T0	45.6 ± 17.3	0.048	82.5 ± 23.5	< 0.001	1.41 [0.63–2.32]	0.69
T1 or 2	54.8 ± 16.3		57.3 ± 23.7		1.29 [0.74–2.44]
C0	44.6 ± 19.6	0.016	84.5 ± 30.1	0.098	0.60 [0.44–1.07]	< 0.001
C1	44.7 ± 15.9		76.1 ± 23.5		1.50 [0.99–2.04]
C2	58.3 ± 13.7		66.6 ± 21.9		2.30 [1.70–4.89]
JHC I	42.5 ± 17.7	0.005	85.5 ± 24.8	< 0.001	1.10 [0.57–1.84]	0.10
JHC II or III	53.7 ± 15.2		66.2 ± 23.2		1.70 [0.96–2.55]
ISKDC I or II	43.8 ± 20.2	0.22	87.7 ± 28.5	0.020	0.67 [0.45–1.12]	0.0052
ISKDC III or IV	49.3 ± 16.2		72.2 ± 23.6		1.70 [0.98–2.49]

HSPN Henoch- Schönlein purpura nephritis, eGFR estimated glomerular filtration rate, E endocapillary proliferation, S segmental sclerosis/adhesion, T tubular atrophy/interstitial fibrosis, C cellular or fibrocellular crescents, JHC Japanese histologic classification, ISKDC International Study of Kidney Disease in Children

ISSN: 1471-2369