Table 4 Univariate and multivariate Cox regression analyses of factors associated with renal outcome
Variables | Univariate model | P value | Multivariate model 1 | P value | Multivariate model 2 | P value |
|---|---|---|---|---|---|---|
HR (95%CI) | HR (95%CI) | HR (95%CI) | ||||
Age (per 10 years) | 1.64 [1.17–2.30] | 0.0040 | 1.58 [1.15–2.18] | 0.0052 | 1.57 [1.12–2.21] | 0.0095 |
Sex (male) | 3.04 [0.93–9.91] | 0.065 | 2.56 [0.75–8.73] | 0.13 | 2.92 [0.74–11.6] | 0.13 |
Diabetes | 1.21 [0.16–9.44] | 0.85 | ||||
Hypertension | 1.30 [0.42–3.97] | 0.65 | ||||
eGFR (per 10 mL/min/1.73 m2) | 0.91 [0.73–1.14] | 0.41 | ||||
mPSL therapy | 1.53 [0.47–4.98] | 0.48 | ||||
Proteinuria (≥ 1 g/day) | 2.16 [0.59–7.88] | 0.24 | 0.49 [0.099–2.43] | 0.38 | 0.52 [0.11–2.42] | 0.41 |
E1 lesion | 6.13 [1.36–27.7] | 0.018 | 8.94 [1.44–55.7] | 0.019 | 6.71 [1.06–42.7] | 0.044 |
S1 lesion | 1.58 [0.52–4.84] | 0.42 | ||||
T1 and 2 lesions | 2.13 [0.69–6.52] | 0.19 | 2.57 [0.67–9.77] | 0.17 | ||
C1 lesion (vs. C0 lesion) | 5.85 [0.74–46.2] | 0.094 | 2.88 [0.29–29.1] | 0.37 | ||
C2 lesion (vs. C0 lesion) | 6.08 [0.62–59.3] | 0.12 | 2.76 [0.23–33.2] | 0.42 | ||
JHC II or III (vs. JHC I) | 1.39 [0.46–4.14] | 0.56 | ||||
ISKDC grade III or IV lesion (vs. grade I or II) | 5.09 [0.66–39.1] | 0.12 |