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Fig. 4 | BMC Nephrology

Fig. 4

From: The two isoforms of matrix metalloproteinase- 2 have distinct renal spatial and temporal distributions in murine models of types 1 and 2 diabetes mellitus

Fig. 4

Immunohistochemical staining of kidneys from FL-MMP-2 and NTT-MMP-2 in the db/db model of Type 2 diabetes mellitus. Panel I. There is a low basal expression of FL-MMP-2 and NTT-MMP-2 in the cortex of control db/m kidneys. Staining for both isoforms increases in the db/db kidneys at 10 and 16 weeks. Panel lI. Semi-quantitative scoring of IHC staining. (N = 8 for each group; * p < 0.05; X10)

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BMC Nephrology

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