|
CEBAM
|
ACP
|
HAS
|
KDIGO
|
KHA-CARI
|
BCMA
|
UMHS
|
VA-DoD
|
NICE
|
---|
2012
|
2013
|
2013
|
2013
|
2013
|
2014
|
2014
|
2014
|
2015
|
---|
Diagnostic Tests in newly diagnosed CKD
|
clinical blood tests
|
blood pressure
| | | | |
▪
| | | | |
serum creatinine
| | |
▪
|
▪
|
▪
| | | | |
(e)GFR (creatinine)
|
*
| |
▪
| |
▪
|
▪
|
▪
|
▪
|
▪
|
blood count
| | |
▪
| |
▪
| | | | |
serum urea
| | |
i
| |
▪
| | | | |
serum uric acid
| | |
▪
| | | | | | |
serum albumin
| | |
i
| |
▪
| | | | |
serum electrolytes
| | |
▪
| |
▪
| | | | |
serum glucose
| | |
▪
| |
▪
| | | | |
lipids
| | |
▪
| |
▪
| | | | |
serum cystatin C
| | | |
i
| | | | | |
eGFR (cystatin C)
| | | | | | | | |
i
|
clearance
| | | |
i
| | | | | |
HbA1c
| | | | | | | | | |
serum calcium
| | |
▪
| |
i
| | | | |
serum phosphate
| | | | |
i
| | | | |
serum phosphorus
| | |
i
| | | | | | |
serum PTH
| | |
▪
| |
i
| | | | |
serum 25-hydroxy-Vitamin D
| | |
▪
| |
i
| | | | |
iron
| | | | |
i
| | | | |
serum electrophoresis
| | |
i
| |
i
| | | | |
ANA
| | |
i
| |
i
| | | | |
anti-ENA
| | | | |
i
| | | | |
complement
| | |
i
| |
i
| | | | |
Hepatitis-B serology
| | | | |
i
| | | | |
Hepatitis-C serology
| | | | |
i
| | | | |
HIV-serology
| | | | |
i
| | | | |
anti-GBM
| | |
i
| |
i
| | | | |
ANCA
| | |
i
| |
i
| | | | |
inulin
| | | | | | | | |
i
|
51Cr-EDTA
| | | | | | | | |
i
|
125I-iothalamate
| | | | | | | | |
i
|
iohexol
| | | | | | | | |
i
|
urine tests
|
albuminuria
| | |
▪
|
▪
|
i
| |
▪
|
▪
|
–
|
proteinuria - reagent strips
| | | | | | | | |
- ***
|
urine albumin-creatinin-ratio (ACR)
|
▪**
| | | |
i
|
▪
| | |
n
|
urine protein-creatinin ratio (PCR)
|
▪**
| | | | | | | |
i
|
urine leucocytes
| | |
▪
| | | | | | |
hematuria
| | |
▪
|
(▪) ****
| | | | |
unclear*****
|
urine microscopy
| | | | |
▪
| | | |
(−)
|
24 h urine
| | |
i
| | | | | | |
urine electophoresis
| | | | |
i
| | | | |
imaging
|
renal ultrasound
|
i
| |
▪
| |
▪
| |
i
|
▪
|
i
|
bladder ultrasound
| | |
i
| | | | | | |
MRI
| | | | | | | | | |
CT
| | | | | | | | | |
Angiography
| | | | | | | | | |
renal artery doppler
| | |
i
| | | |
i
| | |
invasive
|
kidney biopsy
| | |
i
| | | | | | |
- ▪ recommendation, − negative recommendation, i: when indicated, *implicitly mentioned, **ACR or PCR, ***unless able to detect microalbuminuria, ****no explicitly formulated recommendation, but mentioned in background and a flow diagram, *****opportunistic detection
- ANA anti-nuclear antibodies, anti-ENA anti extractable nuclear antibodies, ANCA anti-neutrophil cytoplasmic antibodies, anti-GBM anti-glomerular basement membrane antibodies, eGFR estimated glomerular filtration rate, PTH parathyroid hormone
- American College of Physicians (ACP), Belgisch Centrum voor Evidence Based Medicine (CEBAM), British Columbia Medical Association (BCMA), Department of Veteran’s Affairs (VA-DoD), Haute Autorité de Santé (HAS), Kidney Disease Improving Global Outcomes (KDIGO), Kidney Health Australia - Caring for Australasians with Renal Impairment (KHA-CARI), National Institute of Health and Care Excellence (NICE), University of Michigan Health System (UMHS)