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Table 9 Recommendation summary - anemia management

From: Diagnosis and management of non-dialysis chronic kidney disease in ambulatory care: a systematic review of clinical practice guidelines

  CEBAM ACP HAS KDIGO KHA-CARI BCMA UMHS VA-DoD NICE
2012 2013 2013 2013 2013 2014 2014 2014 2015
Management of anemia
 diagnosis definition      
  lower limit in g/dl 11    M: 13, F: 12    M: 13, F: 12   11
 monitoring monitor for anemia    i   
  tests       
  frequency (per year) individual    1–4      
 initial evaluation          
 treatment options iron   i      
  erythropoetin   i       
  nutritional supplements    i       
  androgens          
  blood transfusion    −/i*       
 treatment indications         
  target values         
  monitoring         
  erythropoietine resistance         
  referral         
  1. ▪ recommendation, − negative recommendation, F: female, M: male, i: when indicated, *Transfusions should be avoided (risk of allo-immunization). The only indications are symptomatic anemia in patients with an associated risk factor; acute worsening of anemia by blood loss (hemorrhage, surgery), hemolysis or resistance to erythropoietin. A search for anti-HLA antibodies should be performed before and after any transfusion in patients waiting for kidney transplant
  2. American College of Physicians (ACP), Belgisch Centrum voor Evidence Based Medicine (CEBAM), British Columbia Medical Association (BCMA), Department of Veteran’s Affairs (VA-DoD), Haute Autorité de Santé (HAS), Kidney Disease Improving Global Outcomes (KDIGO), Kidney Health Australia - Caring for Australasiansians with Renal Impairment (KHA-CARI), National Institute of Health and Care Excellence (NICE), University of Michigan Health System (UMHS)