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Fig. 2 | BMC Nephrology

Fig. 2

From: AL amyloidosis with non-amyloid forming monoclonal immunoglobulin deposition; a case mimicking AHL amyloidosis

Fig. 2

Schematic diagrams of the two-LC-MS/MS analyses. a LMD-LC-MS/MS identified mu heavy-chain and kappa light-chain. The identified peptide sequences were identical to amino acid position 79–89, 121–128, 132–150, 164–177, 244–238, and 377–391 of mu heavy-chain, position 1–18 and 47–55 of kappa light-chain variable domain, and position 41–75 and 83–99 of kappa light-chain constant domain. b LC-MS/MS of isolated amyloid fibrils only identified kappa light-chain. The identified peptide sequences were identical to amino acid position 1–18 and 47–55 of kappa light-chain variable domain

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