Table 1 Baseline characteristics in AS and control groups
Variables | Alport group | Matched Control group | p value |
|---|---|---|---|
N | 21 | 41 | |
Recipient age | 22 (15–56) | 23 (9–71) | 0.94 |
Recipient gender (Male) | 15 (71.4%) | 27 (65.9%) | 0.78 |
Recipient BMI | 18.3 (14.4–22.9) | 20.2 (14.6–27.2) | 0.083 |
Time on Dialysis (month) | 12 (0–193) | 25 (0–137) | 0.070 |
RRT modality (HD) | 17 (81.0%) | 33 (80.5%) | 1.0 |
Donor age | 52 (40–65) | 50 (16–78) | 0.42 |
Donor gender (Male) | 15 (71.4%) | 15 (37.5%) | 0.015* |
No. of Transplantation | |||
first | 20 (95.2%) | 40 (97.5%) | 1.00 |
second | 1 (4.8%) | 1 (2.4%) | NA |
third | 0 (0.0%) | 0 (0.0%) | |
HLA-mismatch | |||
Class I | 1.33 ± 0.73 | 1.46 ± 0.71 | 0.46 |
Class II | 0.62 ± 0.59 | 0.78 ± 0.42 | 0.17 |
ABO incompatible | 5 (23.8%) | 9 (22.0%) | 1.0 |
Graft weight | 170 (125–280) | 175 (120–270) | 0.50 |
WIT (min) | 5 (0–15) | 5 (0–24) | 0.67 |
TIT (min) | 73 (39–660) | 67.5 (44–2233) | 0.55 |
Preformed DSAa | |||
HLA-Class I | 0/9 (0.0%) | 5/21 (23.8%) | 0.30 |
HLA-Class II | 0/6 (0.0%) | 3/19 (15.8%) | 1.0 |
Graft failure | 6 (28.6%) | 19 (45.2%) | 0.27 |
Chronic rejection | 4 | 14 | 0.89 |
Non-compliance | 1 | 1 | 0.073 |
Unknown | 1 | 4 | NA |
Follow up period (month) | 83 (5–315) | 110 (0–348) | 0.78 |
Living donor RTx | 19 (90.5%) | 38 (92.7%) | 1.0 |
Era of transplantation | |||
-1989 | 3 (14.3%) | 5 (12.2%) | 1.0 |
1990–1999 | 4 (19.0%) | 11 (26.8%) | 0.55 |
2000–2009 | 6 (28.5%) | 18 (43.9%) | 0.28 |
2010- | 8 (38.1%) | 7 (17.1%) | 0.12 |
Hematuriab | 2/18 (11.1%) | 5/25 (20.0%) | 0.69 |