Long-term survival in Japanese renal transplant recipients with Alport syndrome: a retrospective study

Katsuma, Ai; Nakada, Yasuyuki; Yamamoto, Izumi; Horita, Shigeru; Furusawa, Miyuki; Unagami, Kohei; Katsumata, Haruki; Okumi, Masayoshi; Ishida, Hideki; Yokoo, Takashi; Tanabe, Kazunari

doi:10.1186/s12882-018-1052-9

BMC Nephrology

Table 3 Twenty-one kidney transplantation recipients with Alport syndrome

From: Long-term survival in Japanese renal transplant recipients with Alport syndrome: a retrospective study

Case No.	Living/Cadaver	ABO-compatibility	Recipient	Donor		f/u period (month)	UP^a	Hematuria^b	Latest creatinine in serum	Recurrence of AS^c	Graft loss	Causes of graft loss
Case No.		ABO-compatibility	Age	Type/Relation	Age	f/u period (month)	UP^a	Hematuria^b	Latest creatinine in serum	Recurrence of AS^c	Graft loss	Causes of graft loss
1	Living	Incompatible	26–30	Father	56–60	36	(+)	(−)	Loss	(−)	(+)	CR
2	Living	Compatible	26–30	Father	46–50	131	(−)	(−)	1.59		(−)
3	Living	Incompatible	16–20	Father	41–45	5	(−)	unknown	1.16		(−)
4	Living	Compatible	56–60	Husband	56–60	12	(−)	(−)	0.78		(−)
5	Living	Incompatible	16–20	Mother	46–50	110	(−)	unknown	Loss		(+)	CR
6	Living	Compatible	26–30	Mother	56–60	5	(−)	(+)	1.06		(−)
7	Living	Compatible	21–25	Father	46–50	290	(+)	(−)	Loss		(+)	CR
8	Living	Compatible	26–30	Father	56–60	276	(−)	(−)	1.95		(−)
9	Living	Compatible	21–25	Father	56–60	239	(+)	(−)	1.62		(−)
10	Living	Compatible	16–20	Father	46–50	216	(−)	unknown	1.4		(−)
11	Living	Compatible	21–25	Father	56–60	180	(−)	(−)	2.17	(−)	(−)
12	Living	Compatible	22–25	Father	56–60	120	(+)	(−)	Loss	(−) TBMD	(+)	CR
13	Living	Compatible	31–35	Father	56–60	83	(−)	(−)	1.31		(−)
14	Living	Incompatible	21–25	Father	51–55	47	(−)	(−)	1.32		(−)
15	Living	Incompatible	21–25	Father	46–50	24	(−)	(−)	1.16	(−)	(−)
16	Living	Compatible	21–25	Father	46–50	11	(−)	(−)	1.44	(−) TBMD	(−)
17	Living	Compatible	16–20	Mother	51–55	204	(−)	(−)	1.35		(−)
18	Living	Compatible	21–25	Mother	46–50	39	(+)	(−)	Loss		(+)	NC
19	Living	Compatible	21–25	Mother	46–50	56	(−)	(+)	1.58	(−)	(−)
20	Cadaver	Compatible	16–20	Other	36–40	315	(+)	(−)	Loss		(+)	unknown
21	Cadaver	Compatible	41–45	Other	61–65	35	(−)	(−)	1.92		(−)

KTx kidney transplantation, Bx allograft biopsy, AS Alport syndrome, N.D. no data, f/u follow up, UP urine proteinuria, NC non-compliance, CR chronic rejection, TBMD thin basement membrane disease. ^aPositive of urine proteinuria was defined as more than one plus by urinary qualitative examination. ^bPositive hematuria was defined as more than one plus at the latest examination. ^cRecurrence of AS was defined as no appearance of a deficiency of collagen α5 in glomerular basement membrane

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