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Table 6 Comparison of median percent fluid overload upon initiation of CRRT in all patients, survivors, and non-survivors between eras (median (inter-quartile range)), as well as over the 10-year study period

From: Pediatric continuous renal replacement therapy: have practice changes changed outcomes? A large single-center ten-year retrospective evaluation

Principal Diagnosis 2004–2008 2009–2013 2004–2013
All Patients Survivors Non-survivors All Patients Survivors Non-survivors All Patients Survivors Non-survivors
Cardiac 19 (2, 26) 5 (2, 22) 20 (19, 33) 4 (3, 11) 12 (3,29) 4 (0, 7) 7 (2, 22) 9 (3, 24) 7 (0, 20)
Renal 10 (6, 30) 10 (6, 30) 23 (13, 30) 17 (13, 30) 28 (28,28) 20 (12, 30) 17 (11, 30) 28 (28, 28)
Liver 20 (15, 31) 37 (17, 42) 18 (14, 24) 20 (12, 30) 19 (12, 30) 20 (12, 30) 20 (12, 30) 20 (12, 35) 19 (13, 27)
Hematology/ Oncology 15 (8, 22) 20 (12, 22) 12 (8, 15) 17 (5, 29) 14 (0, 29) 21 (5, 29) 17 (8, 28) 17 (8, 22) 16 (8, 29)
Bone marrow transplant 16 (10, 20) 15 (9,20) 16 (10, 20) 10 a (7, 12) 9 (7, 11) 10 (7, 13) 11 (9, 18) 10 (8, 12) 11 (10, 19)
Pulmonary 15 (9, 18) 20 (5, 26) 15 (11, 15) 13 (4, 22) 13 (8, 18) 13 (0, 25) 15 (7, 19) 18 (8, 20) 15 (7, 16)
Inborn Error of Metabolism 0 (0, 0) 0 (0, 0) 0 (0, 16) 0 (0, 0) 17 (0, 35) 0 (0, 16) 0 (0, 0) 17 (0, 35)
Sepsis 20 (9, 28) 8 (0, 21) 25 (13, 30) 22 (20, 38) 17 (12, 22) 38 (20, 46) 21 (12, 30) 12 (8, 21) 27 b (19, 34)
Neonates 20 (9, 32) 21 (8, 39) 20 (20, 20) 14 (0, 26) 6 (0, 14) 26 b (14, 37) 14 (6, 29) 10 (0, 15) 23 (14, 37)
Other c 21 (13, 40) 21 (13, 28) 28 (12, 48) 11 (4, 21) 17 (5, 21) 4 (0, 12) 17 (8, 30) 17 (10, 28) 12 (4, 36)
  1. a p < 0.05 comparing all patient median percent fluid overload between the 2004–2008 and 2009–2013 cohorts
  2. b p ≤ 0.05 comparing median percent fluid overload between survivors and non-survivors within the respective cohort period
  3. c Includes rheumatologic, gastroenterologic, multiple organ, neurologic, ingestions, hemorrhage, rhabdomyolysis, and non-accidental trauma