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Table 1 Cohort characteristics among Cases and Controls in Norway, 1988–2013

From: Low birth weight associates with glomerular area in young male IgA nephropathy patients

 

IgAN controls

IgAN cases

IgAN cases combined

Neither LBW nor SGA

LBW but not SGA

SGA but not LBW

Both LBW and SGA

LBW and/or SGA

N

18

11

10

12

33

N (%) male

8 (44.4)

5 (45.5)

5 (50.0)

6 (50.0)

16 (48.5)

Age at Biopsy (years)

22.8 ± 9.0

21.1 ± 8.6

22.3 ± 7.1

28.3 ± 8.9

24.1 ± 8.7

Weight at Biopsy (Kg)

76.8 ± 22.6

56.8 ± 27.9

68.3 ± 18.6

75.2 ± 14.3

66.1 ± 21.8

Systolic BP (mmHg)

124.4 ± 22.9

118.8 ± 16.2

131.3 ± 9.8

126.1 ± 17.5

124.8 ± 15.6

Diastolic BP (mmHg)

76.6 ± 13.2

72.6 ± 14.9

77.8 ± 10.1

72.7 ± 11.1

74.0 ± 12.2

eGFR (ml/min/1.73m2)

94.8.0 ± 27.3

99.4 ± 32.9

95.5 ± 23.5

92.1 ± 18.6

95.5 ± 25.0

Urinary Protein (g/d)

1.8 ± 1.7

1.7 ± 1.5

1.0 ± 1.3

2.4 ± 2.6

1.7 ± 1.9

Birth Weight (kg)

3.6 ± 0.53

1.9 ± 0.75b

2.9 ± 0.17a

2.4 ± 0.42b

2.4 ± 0.65b

Gestational age (week)

40.3 ± 1.1

32.6 ± 4.5b

40.40 ± 0.70

38.7 ± 1.2b

37.2 ± 4.3b

Birthweight for Gestational Age (Z-score)

−0.18 ± 1.04

− 0.28 ± 0.73

−1.56 ± 0.24b

−2.19 ± 0.54b

− 1.36 ± 0.98b

Maternal Pre-eclampsia

0 (0.0)

0 (0.0)

2 (20.0)

2 (16.7)

4 (12.1)

Maternal pregestational diseaseb

0 (0.0)

0 (0.0)

0 (0.0)

1 (8.3)

1 (3.0)

  1. apvalue< 0.01,bp-value< 0.001 as compared to IgAN controls
  2. bMaternal pregestational disease was defined as maternal rheumatic disease, renal disease, diabetes mellitus or hypertension