Table 3 Comparison of clinical, birth-related and glomerular histomorphometric characteristics between normal controls and IgAN controls
From: Low birth weight associates with glomerular area in young male IgA nephropathy patients
Normal controls | IgAN controls | ||
|---|---|---|---|
Not LBW or SGA | Not LBW or SGA | p-value | |
N | 19 | 18 | |
N (%) Male | 10 (52.6) | 8 (44.4) | 1.0 |
Age at Biopsy (years) | 21.8 ± 8.6 | 22.8 ± 9.0 | 0.7 |
Systolic BP (mmHg) | 114.7 ± 15.6 | 124.4 ± 22.9 | 0.1 |
Diastolic BP (mmHg) | 71.3 ± 13.8 | 76.6 ± 13.2 | 0.2 |
eGFR (ml/min/1.73m2) | 92.5 ± 28.4 | 94.8 ± 27.3 | 0.8 |
Urinary protein (g/d) | 0.32 ± 0.28 | 1.8 ± 1.7a | 0.002 |
Birth Weight (kg) | 3.7 ± 0.5 | 3.6 ± 0.5 | 0.4 |
Gestational age (week) | 39.9 ± 1.4 | 40.3 ± 1.1 | 0.3 |
Birth weight for gestational age (Z-score) | 0.25 ± 0.99 | −0.18 ± 1.04 | 0.2 |
Glomerular tuft volume (μm3 ×106) c | 1.97 ± 0.77 | 2.37 ± 0.82 | 0.1 |
Glomerular tuft area (μm2) | 12,522 ± 3410 | 14,036 ± 3502 | 0.1 |
Glomerular tuft diameter (μm) c | 125.0 ± 18.2 | 132.7 ± 16.8 | 0.2 |
Glomerular Density (N per 106 μm2) | 3.29 ± 1.40 | 2.96 ± 0.85 | 0.4 |