Table 1 Patient’s baseline characteristics and comparison according to the development of AKI
Characteristic | Baseline (n = 450) | KDIGO | ||
|---|---|---|---|---|
No AKI (n = 349) | AKI (n = 101) | p value | ||
Age (years) - mean ± SD | 62 ± 16 | 60.6 ± 15.7 | 71.1 ± 13.2 | < 0.0001 |
Gender (Male) – n (%) | 227 (50.4) | 168 (48.1%) | 59 (58.4%) | 0.069 |
Race (Caucasian) – n (%) | 431 (95.8) | 335 (96) | 96 (95) | 0.679 |
Co-morbidities – n (%) | ||||
Hypertension | 225 (50) | 168 (48.1) | 57 (56.4) | 0.142 |
Diabetes | 84 (18.7) | 62 (17.8) | 22 (21.8) | 0.001 |
CVD | 29 (6.4) | 13 (3.7) | 16 (15.8) | < 0.0001 |
COPD | 25 (5.6) | 13 (3.7) | 12 (11.9) | < 0.0001 |
Cirrhosis | 9 (2) | 7 (2) | 2 (1.9) | 0.987 |
Neoplasia | 190 (42.2) | 135 (38.7) | 55 (54.5) | 0.005 |
SAPS II - n (%) | 23 (17.4) | 19.1 (10.9) | 34.3 (21.3) | < 0.0001 |
Baseline SCr (mg/dl) - mean ± SD | 1 ± 0.5 | 0.9 ± 0.4 | 1.2 ± 0.7 | < 0.0001 |
Baseline eGFR (ml/min/1.73 m2) - mean ± SD | 80.3 ± 1.1 | 92.5 ± 1.2 | 60.5 ± 1.3 | < 0.0001 |
Hemoglobin (g/dl) - mean ± SD | 11.1 ± 1.7 | 11.3 ± 1.7 | 10.5 ± 1.6 | < 0.0001 |
Post-operative neutrophils - mean ± SD | 9.2 ± 4.2 | 9.39 ± 4.35 | 8.61 ± 3.57 | 0.102 |
Post-operative lymphocytes - mean ± SD | 1.2 ± 0.8 | 1.26 ± 0.90 | 0.97 ± 0.61 | 0.003 |
Post-operative platelets - mean ± SD | 243.1 ± 105.2 | 245.95 ± 104.94 | 233.05 ± 106.2 | 0.279 |
Post-operative NL/P - mean ± SD | 4.78 ± 4.64 | 4.33 ± 3.36 | 6.36 ± 7.34 | < 0.001 |
Post-operative NL/P > 4.86– n (%) | 154 (34.2) | 113 (32.4) | 54 (53.5) | < 0.001 |
Pre-operative sepsis – n (%) | 70 (15.6) | 39 (11.2) | 31 (30.7) | < 0.001 |
Mechanical ventilation – n (%) | 11 (2.4) | 6 (1.7) | 5 (4.9) | 0.064 |
Vasopressors – n (%) | 80 (17.7) | 55 (15.8) | 25 (24.8) | 0.037 |
Fluid balance in the first 48 h (L) - mean ± SD | 1.48 ± 1.43 | 1.40 ± 1.42 | 1.72 ± 1.44 | 0.046 |
LOS in hospital (days) - mean ± SD | 12 ± 12.6 | 11.1 ± 11.3 | 15.2 ± 16.1 | 0.004 |
LOS in ICU (days) - mean ± SD | 20 ± 4.4 | 3.6 ± 7.1 | 6.9 ± 11.7 | < 0.0001 |
Hospital mortality – n (%) | 29 (6.4) | 8 (2.3) | 21 (20.8) | < 0.0001 |