Skip to main content

Table 2 Patient and procedural characteristics and association with Gal-3 terciles

From: Elevated preoperative Galectin-3 is associated with acute kidney injury after cardiac surgery

Patient characteristics

Overall

1st Tercile

2nd Tercile

3rd Tercile

p value

KDIGO

 No AKI

67.9%

73.4%

70.5%

59.6%

< 0.001

 Stage 1

26.3%

22.9%

24.6%

31.6%

 

 Stage 2

4.5%

2.6%

4.2%

6.9%

 

 Stage 3

1.3%

1.2%

0.8%

1.8%

 

Agea

65.7 ± 9.9

63.6 ± 10.0

65.5 ± 9.6

66.8 ± 10.6

0.464

Female

22.7%

18.2%

20.6%

32.0%

< 0.001

BMIa

29.6 ± 5.5

29.6 ± 5.2

29.6 ± 5.5

29.8 ± 5.9

0.464

BSAa

2.0 ± 0.2

2.0 ± 0.3

2.1 ± 0.2

2.0 ± 0.3

0.464

Smoker

21.4%

24.4%

22.2%

21.4%

0.488

Atrial fibrillation

6.5%

5.4%

6.2%

8.7%

0.082

CHF

11.2%

7.3%

8.7%

15.9%

< 0.001

Last pre-op serum creatinine (mean, SD)

1.1 ± 0.6

1.1 ± 0.5

1.1 ± 1.4

1.3 ± 1.0

0.464

Diabetes

38.0%

34.6%

33.9%

43.8%

0.001

Ejection fraction < 40%

12.1%

10.6%

10.0%

12.3%

0.508

Hypertension

81.0%

79.2%

80.1%

83.0%

0.273

IABP pre-op

3.8%

4.6%

4.8%

2.7%

0.165

Prior MI

 No

54.6%

57.3%

57.4%

53.7%

0.098

  < 24 h pre-op

1.5%

1.4%

1.5%

2.1%

 

  > 24 h & < 7 days pre-op

20.5%

18.7%

19.6%

18.0%

 

  > 7 days & < 365 days pre-op

9.8%

7.9%

8.45%

13.6%

 

  > 365 days pre-op

13.6%

14.7%

12.7%

12.6%

 

Vascular disease

27.8%

26.1%

25.2%

30.2%

0.154

Unstable angina

58.2%

53.7%

55.0%

58.1%

0.347

COPD

12.6%

11.2%

12.1%

15.5%

0.095

Left main, ≥50% stenosis

31.5%

33.0%

35.3%

33.0%

0.669

Prior CABG

2.4%

2.3%

2.8%

1.8%

0.566

Prior PCI

19.6%

20.5%

18.7%

20.0%

0.760

Priority

 Emergent

1.5%

2.5%

1.7%

1.6%

0.815

 Urgent

70.1%

68.0%

67.4%

67.8%

 

 Non-urgent

28.3%

29.5%

30.8%

30.6%

 

Received pRBC units

 

30.4%

35.5%

48.6%

< 0.001

Number of pRBC units given pre-op

 0

97.9%

99.4%

97.5%

97.1%

0.142

 1 or more

2.1%

0.6%

2.5%

2.9%

 
  1. a(Mean, SD)
  2. AKI acute kidney injury, KDIGO Kidney Disease: Improving Global Outcomes, BMI, body mass index (kg/m2), BSA body surface area (m2), CABG coronary artery bypass graft, CHF congestive heart failure, COPD chronic obstructive pulmonary disease, IABP intra-operative balloon pump, MI myocardial infarction, PCI percutaneous coronary intervention, RBC red blood cell, SD standard deviation