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Table 3 Unadjusted and STS adjusted model evaluating preoperative Gal-3 measurements and association with KDIGO stage severity

From: Elevated preoperative Galectin-3 is associated with acute kidney injury after cardiac surgery

 

KDIGO Stage 1

KDIGO Stage 2 or 3

OR

95% CI

p value

OR

95% CI

p value

Unadjusted

Preoperative

1.03

1.01–1.04

0.000

1.04

1.02–1.06

0.000

Natural log

1.47

1.19–1.81

0.000

2.03

1.40–2.94

0.000

Tertiles

 1

1.00

1.00–1.00

 

1.00

1.00–1.00

 

 2

1.12

0.83–1.50

0.456

1.36

0.74–2.52

0.322

 3

1.70

1.28–2.27

0.000

2.86

1.63–5.01

0.000

Preoperative above median

1.36

1.08–1.72

0.009

2.44

1.53–3.89

0.000

STS Readmission Prediction Modela

Preoperative

1.03

1.01–1.04

0.002

1.03

1.00–1.06

0.005

Natural log

1.40

1.10–1.78

0.006

1.87

1.23–2.86

0.004

Tertiles

 1

1.00

1.00–1.00

 

1.00

1.00–1.00

 

 2

1.08

0.79–1.48

0.625

1.37

0.73–2.56

0.329

 3

1.71

1.24–2.37

0.001

2.95

1.63–5.34

0.000

Preoperative above median

1.30

1.00–1.68

0.046

2.31

1.39–3.85

0.001

STS Readmission Prediction Model + NT-pro BNP

Preoperative

1.02

1.01–1.04

0.005

1.03

1.00–1.06

0.007

Natural log

1.31

1.03–1.68

0.028

1.73

1.13–2.65

0.012

Tertiles

 1

1.00

1.00–1.00

 

1.00

1.00–1.00

 

 2

1.08

0.79–1.48

0.631

1.36

0.72–2.57

0.337

 3

1.65

1.19–2.29

0.003

2.85

1.57–5.16

0.001

Preoperative above median

1.28

0.99–1.66

0.060

2.26

1.35–3.76

0.002

  1. aModel adjusts for variables included in the STS readmission prediction model
  2. KDIGO Kidney Disease: Improving Global Outcomes, CI confidence interval, OR odds ratio, STS Society of Thoracic Surgeons