Systolic and diastolic dysfunction affects kidney outcomes in hospitalized patients

BMC Nephrology

Table 5 Continuous NRI and IDI indices when the echocardiographic parameters are added in the AKI- or ESRD-predicting model

Outcome	Parameter	cNRI (95% CI)	P*	IDI (95% CI)	P*
AKI	Model 1	0.109 (− 0.038–0.256)	0.145	0.008 (0.000–0.002)	0.053
	Model 2	0.211 (0.065–0.356)	0.005	0.001 (0.000–0.002)	0.013
	Model 3	0.148 (0.000–0.295)	0.049	0.002 (0.001–0.004)	0.001
3-year ESRD	Model 1	0.283 (−0.154–0.720)	0.204	0.000 (−0.000–0.001)	0.423
	Model 2	0.477 (0.077–0.876)	0.019	0.002 (0.000–0.003)	0.008
	Model 3	0.685 (0.314–1.055)	< 0.001	0.003 (0.001–0.005)	< 0.001

Reference model: age, sex, body mass index, diabetes, ischemic heart disease, and cerebrovascular disease
Model 1: reference model plus ejection fraction
Model 2: reference model plus E/e’
Model 3: reference model plus combined parameter
*Difference is calculated in comparison to the reference model. cNRI continuous net reclassification improvement, IDI integrated discrimination improvement, AKI acute kidney injury, ESRD end-stage renal disease

ISSN: 1471-2369