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Table 5 Continuous NRI and IDI indices when the echocardiographic parameters are added in the AKI- or ESRD-predicting model

From: Systolic and diastolic dysfunction affects kidney outcomes in hospitalized patients

Outcome Parameter cNRI (95% CI) P* IDI (95% CI) P*
AKI Model 1 0.109 (− 0.038–0.256) 0.145 0.008 (0.000–0.002) 0.053
Model 2 0.211 (0.065–0.356) 0.005 0.001 (0.000–0.002) 0.013
Model 3 0.148 (0.000–0.295) 0.049 0.002 (0.001–0.004) 0.001
3-year ESRD Model 1 0.283 (−0.154–0.720) 0.204 0.000 (−0.000–0.001) 0.423
Model 2 0.477 (0.077–0.876) 0.019 0.002 (0.000–0.003) 0.008
Model 3 0.685 (0.314–1.055) <  0.001 0.003 (0.001–0.005) <  0.001
  1. Reference model: age, sex, body mass index, diabetes, ischemic heart disease, and cerebrovascular disease
  2. Model 1: reference model plus ejection fraction
  3. Model 2: reference model plus E/e’
  4. Model 3: reference model plus combined parameter
  5. *Difference is calculated in comparison to the reference model. cNRI continuous net reclassification improvement, IDI integrated discrimination improvement, AKI acute kidney injury, ESRD end-stage renal disease