Significance of histological crescent formation in patients with IgA vasculitis (Henoch-Schönlein purpura)-related nephritis: a cohort in the adult Chinese population

Table 7 Renal outcome based on categorical grouping of crescent formation by univariate and multivariate Cox regression

Crescent formation	Renal survival from ESRD or 50% decline in renal function
Crescent formation	Univariate (HR, 95% CI)	P	Multivariate (HR, 95% CI)^a	P
Control	1.0		1.0
Group 1	1.798 (0.928–3.485)	0.082	–	0.281
Group 2	3.192 (1.299–7.844)	0.011^*	–	0.578

^aMultivariate Cox model: multivariate with urinary protein > 1.0 g/d, eGFR < 60 mL/min/1.73 m², glomerular sclerosis > 10%, moderate and severe tubular atrophy/interstitial fibrosis, and immunosuppressive treatment
^*P < 0.05

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