Fig. 3

Kaplan-Meier curves for the event “full clinical remission” based on the M-score (a), E-score (b), S- score(c), T-score (d) and C-score (e). Full clinical remission was defined as urinary protein-creatinine ratio < 0.2 g/g and an eGFR decrease of < 5 ml/min/1.73m². Univariate Cox regression yielded the following p-values: M-score: p = 0.41; E-score: p = 0.46; S-score: p = 0.38; T-score: p = 0.39. Multivariate Cox regression adjusting for GFR and proteinuria at baseline and the treatment arm yielded the following p-values (also given in the figure): M-score: p = 0.33; E-score: p = 0.71; S-score: p = 0.65; T-score: p = 0.39). For the C-score, the proportional hazard assumption was not met