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Table 2 Mean and SD of cognitive scores groups A and B in first and second periods

From: Effect of valerian on cognitive disorders and electroencephalography in hemodialysis patients: a randomized, cross over, double-blind clinical trial

Index group First Period Second Period
Before intervention After intervention Before intervention After intervention
N Mean SD N Mean SD P-value N Mean SD N Mean SD P-value
Orientation Aa 19 9.68 0.58 19 9.95 0.23 0.059 17 9.94 0.24 17 9.94 0.24 1.00
B 20 9.50 1.10 20 9.60 1.00 0.157 20 9.60 1.05 20 9.85 0.27 0.101
P-value 0.923 0.428   0.619 0.641  
Immediate memory Aa 19 2.95 0.23 19 3.00 0.00 0.317 17 3.00 17 3.00 0.00 1.00
B 20 2.75 0.44 20 2.85 0.37 0.157 20 2.75 0.64 20 2.80 0.62 0.317
P-value 0.296 0.428 0.442 0.619  
Concentration and calculation Aa 19 3.58 1.22 19 4.05 1.08 0.014 17 3.71 1.10 17 3.71 1.26 1.00
B 20 3.75 1.25 20 3.75 1.19 1.00 20 3.75 1.37 20 4.05 1.19 0.014
P-value 0.708 0.531 0.940 0.424
Remembrance Aa 19 2.53 0.61 19 2.84 0.37 0.014 17 2.59 0.51 17 2.65 0.49 0.317
B 20 2.40 0.68 20 2.40 0.75 1.00 20 2.35 0.74 20 2.55 0.69 0.046
P-value 0.627 0.095 0.442 0.869
Language and understanding Aa 19 7.53 0.61 19 7.74 0.56 0.102 17 7.65 0.70 17 7.71 0.69 0.564
B 20 7.40 1.00 20 7.55 0.83 0.083 20 7.50 0.89 20 7.65 0.67 0.083
P-value 0.923 0.607 0.729 0.752
Space situation Aa 19 0.47 0.51 19 0.47 0.51 1.00 17 0.41 0.51 17 0.41 0.51 1.00
B 20 0.40 0.50 20 0.40 0.50 1.00 20 0.40 0.50 20 0.45 0.51 0.317
P-value 0.708 0.708 0.964 0.845
Cognitive impairment (general) Aa 19 26.74 2.92 19 28.05 2.01 0.003 17 27.29 2.44 17 27.41 2.57 0.527
B 20 26.20 4.21 20 26.55 4.10 0.068 20 26.35 4.44 20 27.35 3.53 0.005
P-value 0.901 0.461 0.821 0.707
  1. aThe group A took valerian capsules in the first therapeutic period of one month and placebo in the second therapeutic period of one month, and vice versa in group B