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Table 3 Mean difference of cognitive scores before and after intervention in each treatment periods in the groups

From: Effect of valerian on cognitive disorders and electroencephalography in hemodialysis patients: a randomized, cross over, double-blind clinical trial

Index group First Period Second Period
N Mean SD N Mean SD
Orientation Aa 19 0.26 0.56 17 0.00 0.00
B 20 0.10 0.31 20 0.25 0.72
  P-value 0.550 0.442
Immediate memory Aa 19 0.05 0.23 17 0.00 0.00
B 20 0.10 0.31 20 0.05 0.22
  P-value 0.813 0.798
Concentration and calculation Aa 19 0.47 0.70 17 0.00 0.50
B 20 0.00 0.32 20 0.30 0.47
  P-value 0.057 0.177
Remembrance Aa 19 0.32 0.48 17 0.06 0.24
B 20 0.00 0.32 20 0.20 0.41
  P-value 0.113 0.478
Language and understanding Aa 19 0.21 0.53 17 0.06 0.43
B 20 0.15 0.37 20 0.15 0.37
  P-value 0.728 0.684
Space situation Aa 19 0.00 0.00 17 0.00 0.00
B 20 0.00 0.00 20 0.05 0.22
  P-value 1.00 0.798
Cognitive impairment (general) Aa 19 1.32 1.38 17 0.12 0.78
B 20 0.35 0.81 20 1.00 1.17
P-value 0.028 0.030
  1. aThe group A took valerian capsules in the first therapeutic period of one month and placebo in the second therapeutic period of one month, and vice versa in group B