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Fig. 2 | BMC Nephrology

Fig. 2

From: Short-term dexamethasone treatment transiently, but not permanently, attenuates fibrosis after acute-to-chronic kidney injury

Fig. 2

Evaluation of long-term fibrosis development in the ischemic kidneys. UIRI was performed for 21 min at 36 °C, n = 8 in the untreated group, n = 10 in sham, dexamethasone and vehicle treatment groups. Animals were euthanized after treatment (3 weeks after UIRI) and 3 weeks after treatment (6 weeks after UIRI). a: Representative images of collagen I immunostained ischemic kidney tissue (magnification: 100x). b: Histological quantification of collagen I protein in ischemic kidneys (magnification: 50x). c: collagen I gene expression (qPCR). °: p < 0.05 vs. Sham, *: p < 0.05

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