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Fig. 6 | BMC Nephrology

Fig. 6

From: Short-term dexamethasone treatment transiently, but not permanently, attenuates fibrosis after acute-to-chronic kidney injury

Fig. 6

Evaluation of inflammatory and fibroblast markers in the ischemic kidneys. UIRI was performed for 21 min at 36 °C, n = 8 in the untreated group, n = 10 in sham, dexamethasone and vehicle treatment groups. Animals were euthanized after treatment (3 weeks after UIRI) and 3 weeks after treatment (6 weeks after UIRI). a: TNFα gene expression (qPCR). b: F4/80 macrophage/monocyte protein expression with representative Western blots for F4/80/β-actin expression. c: α-SMA fibroblast protein expression with representative Western blots for α-SMA/β-actin expression. °: p < 0.05 vs. Sham, *: p < 0.05

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