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Table 3 Agreement between administrative (ICD-9) diagnosis codes and manual chart reviewa

From: Validating laboratory defined chronic kidney disease in the electronic health record for patients in primary care

Comorbidity

Prevalence (Chart Review)

Prevalence (EHR)

Sensitivitya

Specificitya

Kappa Statistic

p-value ‡

Cerebrovascular disease

10%

8%

100%

98%

0.88

< 0.001

Congestive heart failure

14%

16%

50%

93%

0.45

0.001

Coronary artery disease

18%

22%

82%

100%

0.88

< 0.001

Diabetes mellitus

44%

42%

95%

93%

0.88

< 0.001

Hypertension

78%

86%

91%

100%

0.73

< 0.001

  1. aCalculated for ICD-9 diagnosis of each condition compared to chart review (including clinical notes, ICD-9 diagnoses, laboratory results etc.)
  2. p-values are calculated from Cohen’s Kappa test statistic as an index of interrater agreement between 2 raters on categorical data