Serum heat shock protein 27 levels predict cardiac mortality in hemodialysis patients

BMC Nephrology

Table 5 Uni- and multivariate predictors of sudden death mortality

Parameter	Univariate HR (95% CI)	p	Multivariate HR (95% CI)	p
Age	1.68 (1.12–2.71)	< 0.001	1.30 (0.95–1.76)	< 0.001
Diabetes mellitus	1.54 (0.52–2.67)	0.356
History of MI	1.72 (0.65–2.68)	0.198
LVMI	2.68 (1.87–3.83)	0.285
EF	1.47 (0.83–1.94)	0.002	1.31 (0.79–1.74)	0.008
TOC	2.15 (1.12–3.94)	0.239
TAC	1.37 (0.62–2.56)	0.311
oxLDL	1.71 (0.101–2.98)	0.072	1.46 (0.77–3.18)	0.205
Phosphate	1.19 (0.41–1.99)	0.275
Hemoglobin	1.32 (0.68–2.07)	0.235
Troponin T	1.94 (1.35–2.48)	0.011	1.43 (0.66–2.24)	0.113
CRP	0.95 (0.55–1.62)	0.278
IMT	1.71 (0.41–2.87)	0.312
Number of plaques	1.41 (0.53–2.69)	0.244
HSP-27	3.18 (2.68–3.97)	< 0.001	2.75 (2.37–3.44)	0.001

In multivariate analysis included were all variables with a p value < 0.15 in the univariate analysis. HR hazard ratio; CI confidence interval, MI myocardial infarction, LVMI left ventricular mass index, EF ejection fraction, TOC total oxidant capacity, TAC total antioxidant capacity, oxLDL oxidized LDL, CRP C-reactive protein, IMT intima-media thickness, HSP-27 heat shock protein 27. In the multivariate analyses, parameters with a p ≤ 0.15 were entered

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