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Table 1 Comparison of baseline clinical and laboratory characteristics between CTX and CYA groups

From: Analysis of predictive factors for immunosuppressive response in anti-phospholipase A2 receptor antibody positive membranous nephropathy

Characteristics

CTX group (n = 23)

CYA group (n = 24)

P value

Men, n (%)

16 (69.6)

13 (54.2)

0.28

Age (yrs), mean ± SD

43 ± 12

42 ± 15

0.72

Body mass index (kg/m2), M (P25, P75)

25 (23, 29)

25 (23, 27)

0.87

Serum albumin (g/L), mean ± SD

26.1 ± 5.3

28.0 ± 5.8

0.25

24hUP (g/d), M (P25, P75)

8.28 (3.63, 10.98)

4.73 (3.38, 8.60)

0.14

Nephrotic syndrome, n (%)

14 (60.9)

16 (66.7)

0.68

Scr (μmol/L), mean ± SD

78.7 ± 24.7

71.3 ± 19.0

0.26

eGFR (mL/min per 1.73m2), mean ± SD

103 ± 28

115 ± 24

0.15

Lymphocyte count (×109/L), mean ± SD

2.51 ± 1.04

2.25 ± 0.81

0.32

Anti-PLA2R antibody titer (RU/ml), M (P25, P75)

66.4 (31.5, 192.4)

63.4 (33.6, 174.0)

0.69

Systolic pressure (mmHg), mean ± SD

127 ± 8

127 ± 14

0.995

Diastolic pressure (mmHg), mean ± SD

77 ± 11

78 ± 10

0.75

  1. CTX cyclophosphamide, CYA cyclosporine A, Scr Serum creatinine, eGFR estimated glomerular filtration rate, PLA2R phospholipase A 2 receptor