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Table 4 The relative reduction of 24hUP and anti-PLA2R antibody titer at one, three or six–month’s follow-up in CTX and CYA group patients

From: Analysis of predictive factors for immunosuppressive response in anti-phospholipase A2 receptor antibody positive membranous nephropathy

Characteristics

CTX group (n = 23)

CYA group (n = 24)

P value

Relative reduction of 24hUP (%), M (P25, P75)

 One month

46.8 (7.2, 67.2)

4.6 (−57.2, 32.5)

< 0.01

 Three months

66.9 (30.9, 78.7)

22.7 (−66.0, 46.6)

0.01

 Six months

81.0 (68.0, 95.0)

58.5 (10.8, 79.5)

0.02

Relative reduction of anti-PLA2R titer (%), M (P25, P75)

 One month

94.2 (69.1, 97.3)

54.6 (−34.9, 94.7)

0.03

 Three months

97.0 (84.2, 98.9)

92.3 (−15.5, 96.4)

0.07

 Six months

97.0 (93.0, 99.0)

93.5 (79.3, 97.0)

0.22

  1. CTX cyclophosphamide, CYA cyclosporine A, SCr Serum creatinine, PLA2R phospholipase A 2 receptor, 24hUP 24-h urine protein