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Table 1 Demographic, clinical, and laboratory characteristics at renal biopsy

From: Association of high body mass index with development of interstitial fibrosis in patients with IgA nephropathy

  Total BMI < 18.5 kg/m2 18.5 ≤ BMI<25 kg/m2 25 ≤ BMI<28 kg/m2 BMI ≥ 28 kg/m2 P value
No. of patients 481 50 314 83 33  
Male/Female (%) 193/288 (40.1/59.9) 15/35 (30/70) 116/198 (36.9/63.1) 40/43 (48.2/51.8) 21/12 (63.6/36.4)* 0.004
Age (years) 36.87 ± 11.34 28.28 ± 10.80* 36.63 ± 10.54 42.49 ± 11.90* 37.88 ± 10.19 3.6E-11
BMI (kg/m2) 22.75 ± 3.59 17.34 ± 0.89* 21.85 ± 1.74 26.15 ± 0.83* 31.03 ± 2.52* 3.19E-45
SBP (mmHg) 128.69 ± 18.08 122.96 ± 16.64* 128.75 ± 18,50 131.24 ± 18.03 130.03 ± 14.93 0.036
DBP (mmHg) 80.48 ± 12.30 76.12 ± 10.13* 80.44 ± 12.61 82.69 ± 12.38 81.91 ± 11.00 0.014
Hypertension (%) 125/280 (26.0/74.0) 6/44 (12/88)* 83/230 (26.4/73.6) 28/55 (33.7/66.3) 7/26 (21.2/79.8) 0.043
Gross hematuria (%) 134/459 (29.2/70.8) 23/26 (46.9/53.1)* 95/207 (30.3/69.7) 11/78 (14.1/85.9)* 4/30 (13.3/86.7)* 1.1E-5
eGFR
(ml/min per 1.73m2)
85.92 ± 32.28 103.96 ± 31.92* 84.95 ± 32.60 79.53 ± 28.92 88.98 ± 30.58 6.3E-5
UA (μmol/L) 368.28 ± 118.72 345.67 ± 114.99 360.49 ± 115.41 389.89 ± 115.62* 417.39 ± 145.86* 0.004
SCr (μmol/L) 94.65 ± 42.36 77.39 ± 31.16* 95.57 ± 42.68 101.95 ± 45.19 92.90 ± 41.72 0.005
Proteinuria (g/24 h) 2.06 ± 2.26 1.57 ± 1.75 1.90 ± 1.89 2.83 ± 3.47* 2.61 ± 2.40* 0.005
Hb (g/L) 131.55 ± 21.19 126.48 ± 19.01 130.03 ± 20.72 136.59 ± 22.28* 141.33 ± 21.97* 0.002
Alb (g/L) 38.59 ± 7.50 38.32 ± 7.30 38.43 ± 7.41 38.89 ± 8.65 39.72 ± 5.68 0.581
  1. Abbreviations: BMI body mass index; SBP systolic blood pressure; DBP diastolic blood pressure; eGFR estimated glomerular filtration rate;
  2. UA uric acid; SCr serum creatinine; Hb hemoglobin; Alb albumin
  3. *, P value < 0.05 compared with control group. Patients with normal weight were set as control group