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Table 1 Demographic, clinical, and laboratory characteristics at renal biopsy

From: Association of high body mass index with development of interstitial fibrosis in patients with IgA nephropathy

 

Total

BMI < 18.5 kg/m2

18.5 ≤ BMI<25 kg/m2

25 ≤ BMI<28 kg/m2

BMI ≥ 28 kg/m2

P value

No. of patients

481

50

314

83

33

 

Male/Female (%)

193/288 (40.1/59.9)

15/35 (30/70)

116/198 (36.9/63.1)

40/43 (48.2/51.8)

21/12 (63.6/36.4)*

0.004

Age (years)

36.87 ± 11.34

28.28 ± 10.80*

36.63 ± 10.54

42.49 ± 11.90*

37.88 ± 10.19

3.6E-11

BMI (kg/m2)

22.75 ± 3.59

17.34 ± 0.89*

21.85 ± 1.74

26.15 ± 0.83*

31.03 ± 2.52*

3.19E-45

SBP (mmHg)

128.69 ± 18.08

122.96 ± 16.64*

128.75 ± 18,50

131.24 ± 18.03

130.03 ± 14.93

0.036

DBP (mmHg)

80.48 ± 12.30

76.12 ± 10.13*

80.44 ± 12.61

82.69 ± 12.38

81.91 ± 11.00

0.014

Hypertension (%)

125/280 (26.0/74.0)

6/44 (12/88)*

83/230 (26.4/73.6)

28/55 (33.7/66.3)

7/26 (21.2/79.8)

0.043

Gross hematuria (%)

134/459 (29.2/70.8)

23/26 (46.9/53.1)*

95/207 (30.3/69.7)

11/78 (14.1/85.9)*

4/30 (13.3/86.7)*

1.1E-5

eGFR

(ml/min per 1.73m2)

85.92 ± 32.28

103.96 ± 31.92*

84.95 ± 32.60

79.53 ± 28.92

88.98 ± 30.58

6.3E-5

UA (μmol/L)

368.28 ± 118.72

345.67 ± 114.99

360.49 ± 115.41

389.89 ± 115.62*

417.39 ± 145.86*

0.004

SCr (μmol/L)

94.65 ± 42.36

77.39 ± 31.16*

95.57 ± 42.68

101.95 ± 45.19

92.90 ± 41.72

0.005

Proteinuria (g/24 h)

2.06 ± 2.26

1.57 ± 1.75

1.90 ± 1.89

2.83 ± 3.47*

2.61 ± 2.40*

0.005

Hb (g/L)

131.55 ± 21.19

126.48 ± 19.01

130.03 ± 20.72

136.59 ± 22.28*

141.33 ± 21.97*

0.002

Alb (g/L)

38.59 ± 7.50

38.32 ± 7.30

38.43 ± 7.41

38.89 ± 8.65

39.72 ± 5.68

0.581

  1. Abbreviations: BMI body mass index; SBP systolic blood pressure; DBP diastolic blood pressure; eGFR estimated glomerular filtration rate;
  2. UA uric acid; SCr serum creatinine; Hb hemoglobin; Alb albumin
  3. *, P value < 0.05 compared with control group. Patients with normal weight were set as control group