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Table 2 Pathological characteristics at renal biopsy

From: Association of high body mass index with development of interstitial fibrosis in patients with IgA nephropathy

  Total BMI < 18.5 kg/m2 18.5 ≤ BMI<25 kg/m2 25 ≤ BMI<28 kg/m2 BMI ≥ 28 kg/m2 P value
Oxford Score 390 43 260 67 20  
M0/1 (%) 178/212
(45.64/54.36)
15/28
(34.88/65.12)
121/139
(46.5/53.5)
32/35
(47.76/52.24)
10/10
(50/50)
0.5
E0/1 (%) 243/147
(62.31/37.69)
26/17
(60.47/39.54)
158/102
(60.8/39.2)
42/25
(62.69/27.31)
17/3*
(85/15)
0.194
S0/1 (%) 221/169
(56.67/43.33)
33/10*
(76.74/23.26)
143/117
(55/45)
32/35
(47.76/52.24)
13/7
(65/35)
0.018
T0/1/2 (%) 327/54/9
(83.85/13.85/2.30)
35/6/2
(81.40/13.95/4.65)
214/40/6
(82.3/15.4/2.3)
60/6/1
(89.55/8.96/1.49)
18/2/0
(90/10/0)
0.684
Pathologic lesions 432 44 283 75 30  
Global sclerosis % 11.21 ± 15.31 8.63 ± 12.63 11.72 ± 15.82 10.60 ± 14.43 11.58 ± 16.66 0.628
Segmental sclerosis % 6.82 ± 11.83 4.58 ± 6.86 7.22 ± 13.00 5.77 ± 8.63 8.65 ± 12.90 0.788
Interstitial fibrosis (%)
None 135 (31.25) 18 (40.91) 92 (32.51) 16 (21.33) 9 (30) 0.134
Mild (< 30) 244 (56.48) 21 (47.73) 153 (54.06) 52 (69.33) 18 (60) 0.065
Moderate (30–60) 47 (10.88) 4 (9.09) 34 (12.01) 6 (8) 3 (10) 0.756
Severe (> 60) 6 (1.39) 1 (2.27) 4 (1.41) 1 (1.33) 0 0.879
Crescents % 8.04 ± 13.677 2.61 ± 2.50 2.32 ± 2.38 7.55 ± 13.62 8.19 ± 12.01 0.704
Vasculopathy (%) 202 (46.76) 12 (27.27)* 130 (45.94) 46 (61.33)* 14 (46.67) 0.004
  1. *, P value < 0.05 compared with control group. Patients with normal weight were set as control group