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Table 2 Pathological characteristics at renal biopsy

From: Association of high body mass index with development of interstitial fibrosis in patients with IgA nephropathy

 

Total

BMI < 18.5 kg/m2

18.5 ≤ BMI<25 kg/m2

25 ≤ BMI<28 kg/m2

BMI ≥ 28 kg/m2

P value

Oxford Score

390

43

260

67

20

 

M0/1 (%)

178/212

(45.64/54.36)

15/28

(34.88/65.12)

121/139

(46.5/53.5)

32/35

(47.76/52.24)

10/10

(50/50)

0.5

E0/1 (%)

243/147

(62.31/37.69)

26/17

(60.47/39.54)

158/102

(60.8/39.2)

42/25

(62.69/27.31)

17/3*

(85/15)

0.194

S0/1 (%)

221/169

(56.67/43.33)

33/10*

(76.74/23.26)

143/117

(55/45)

32/35

(47.76/52.24)

13/7

(65/35)

0.018

T0/1/2 (%)

327/54/9

(83.85/13.85/2.30)

35/6/2

(81.40/13.95/4.65)

214/40/6

(82.3/15.4/2.3)

60/6/1

(89.55/8.96/1.49)

18/2/0

(90/10/0)

0.684

Pathologic lesions

432

44

283

75

30

 

Global sclerosis %

11.21 ± 15.31

8.63 ± 12.63

11.72 ± 15.82

10.60 ± 14.43

11.58 ± 16.66

0.628

Segmental sclerosis %

6.82 ± 11.83

4.58 ± 6.86

7.22 ± 13.00

5.77 ± 8.63

8.65 ± 12.90

0.788

Interstitial fibrosis (%)

None

135 (31.25)

18 (40.91)

92 (32.51)

16 (21.33)

9 (30)

0.134

Mild (< 30)

244 (56.48)

21 (47.73)

153 (54.06)

52 (69.33)

18 (60)

0.065

Moderate (30–60)

47 (10.88)

4 (9.09)

34 (12.01)

6 (8)

3 (10)

0.756

Severe (> 60)

6 (1.39)

1 (2.27)

4 (1.41)

1 (1.33)

0

0.879

Crescents %

8.04 ± 13.677

2.61 ± 2.50

2.32 ± 2.38

7.55 ± 13.62

8.19 ± 12.01

0.704

Vasculopathy (%)

202 (46.76)

12 (27.27)*

130 (45.94)

46 (61.33)*

14 (46.67)

0.004

  1. *, P value < 0.05 compared with control group. Patients with normal weight were set as control group