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Table 1 Baseline clinical and laboratory data and UAGT levels of iMN patients, MCD patients, and normal subjects

From: The elevated levels of urinary angiotensinogen are correlated with the severity of idiopathic membranous nephropathy

  iMN (n = 48) MCD (n = 46) Normal (n = 44) P value
Age (years) 53 ± 2 40 ± 2## 41 ± 2 < 0.001**
Sex (male/female) 33/15 25/21 24/20 0.350
BMI (kg/m2) 25.2 ± 0.5 23.0 ± 0.5 22.0 ± 0.6 0.010*
Systolic BP (mmHg) 130.0 ± 2.7 124.5 ± 2.4 120.3 ± 1.1 0.009**
Diastolic BP (mmHg) 80.1 ± 1.8 76.0 ± 1.7 71.9 ± 1.1 0.002**
Uric acid (μmol/L) 356.3 ± 11.0 351.4 ± 10.0 379.6 ± 3.3 0.067
Serum creatinine (μmol/L) 71.2 ± 2.6 65.4 ± 2.0 68.8 ± 2.0 0.041*
Serum albumin (g/L) 29.6 ± 1.0 21.8 ± 1.1## 42.4 ± 0.5 < 0.001**
eGFR (ml/min/1.73m2) 37.1–143.0 (100.0 ± 3.0) 78.0–146.8 (110.0 ± 2.4) 48.9–162.9 (114.6 ± 4.5) 0.008**
Proteinuria (g/d) 6.6 ± 0.7 8.5 ± 0.7 0.100 ± 0.004 < 0.001**
UAGT (μg/g.Cr) 277.1 ± 61.3 241.2 ± 42.4 6.5 ± 0.7 < 0.001**
  1. BMI body mass index, BP blood pressure, eGFR estimated glomerular filtration rate, UAGT urinary angiotensinogen. *P < 0.05, **P < 0.01 among the three groups. ##p < 0.01 between iMN and MCD patients.