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Table 1 Baseline clinical and laboratory data and UAGT levels of iMN patients, MCD patients, and normal subjects

From: The elevated levels of urinary angiotensinogen are correlated with the severity of idiopathic membranous nephropathy

 

iMN (n = 48)

MCD (n = 46)

Normal (n = 44)

P value

Age (years)

53 ± 2

40 ± 2##

41 ± 2

< 0.001**

Sex (male/female)

33/15

25/21

24/20

0.350

BMI (kg/m2)

25.2 ± 0.5

23.0 ± 0.5

22.0 ± 0.6

0.010*

Systolic BP (mmHg)

130.0 ± 2.7

124.5 ± 2.4

120.3 ± 1.1

0.009**

Diastolic BP (mmHg)

80.1 ± 1.8

76.0 ± 1.7

71.9 ± 1.1

0.002**

Uric acid (μmol/L)

356.3 ± 11.0

351.4 ± 10.0

379.6 ± 3.3

0.067

Serum creatinine (μmol/L)

71.2 ± 2.6

65.4 ± 2.0

68.8 ± 2.0

0.041*

Serum albumin (g/L)

29.6 ± 1.0

21.8 ± 1.1##

42.4 ± 0.5

< 0.001**

eGFR (ml/min/1.73m2)

37.1–143.0 (100.0 ± 3.0)

78.0–146.8 (110.0 ± 2.4)

48.9–162.9 (114.6 ± 4.5)

0.008**

Proteinuria (g/d)

6.6 ± 0.7

8.5 ± 0.7

0.100 ± 0.004

< 0.001**

UAGT (μg/g.Cr)

277.1 ± 61.3

241.2 ± 42.4

6.5 ± 0.7

< 0.001**

  1. BMI body mass index, BP blood pressure, eGFR estimated glomerular filtration rate, UAGT urinary angiotensinogen. *P < 0.05, **P < 0.01 among the three groups. ##p < 0.01 between iMN and MCD patients.