Skip to main content

Advertisement

Table 1 Past reports of HUS related to pertussis infection

From: Treatment of hemolytic uremic syndrome related to Bordetella pertussis infection —is plasma exchange or eculizumab use necessary?

  1 2 3 4 5 6 The present case
The Age of Onset 20 days 6 weeks 4 weeks 24 days 2 months 1 month 1 month
Sex M F M F M F F
Duration of Pertussis infection leading to HUS 6 weeks 16 days 21 days 17 days 12 days 18 days 19 days
Intubation + + + + +
LDH 1200 1950 5259 2642 unknown 3268 4428
Plasma therapy PI PI PE PE PI, PE
Dialysis PD HD PD HD
ECZ +
Antibiotics EM CTX, EM AMPC, CTX, CAM AZM AZM PIPC, CTX, CAM PIPC, CAM
Steroid + + +
CH50, C3, C4 Normal Normal Normal Normal Normal Decreased
Gene mutation CFH unknown THBD
Prognosis Death Alive Alive Alive Alive Alive Alive
Follow-up (year) 2 0.6 unknown 1 2.5 3
Author Berner R. et al. [3] Pela I. et al. [11] Chaturvedi S. et al. [4] Obando I. et al. [12] Cohen-Ganelin E. et al. [13] Ito N. et al. [14]  
Reported year 2002 2006 2010 2012 2012 2014 2018
  1. Abbreviations: LDH Lactate dehydrogenase, ECZ Eculizumab, PI Plasma Infusion, PE Plasma Exchange, PD Peritoneal
  2. Dialysis, HD Hemodialysis, EM Erythromycin, CTX Cefotaxime, AMPC Amoxicillin, CAM Clarithromycin,
  3. AZM Azithromycin, PIPC Piperacillin