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Fig. 1 | BMC Nephrology

Fig. 1

From: Association of plasma somatostatin with disease severity and progression in patients with autosomal dominant polycystic kidney disease

Fig. 1

Somatostatin, its precursors and cleavage products (modified from chapter 9 of handbook of physiology by Patel et al. [26]). SST is synthesized as part of a large precursor protein, preproSST, located on the long arm of chromosome 3 and is rapidly cleaved into the prohormone form, proSST. ProSST is further enzymatically processed in two bioactive forms, SST-14 and SST-28 .These forms are both measured in the assay we used. Abbreviations are: SST, somatostatin

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