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Table 2 Potential determinants of SST concentration in ADPKD patients receiving standard care (n = 127)\

From: Association of plasma somatostatin with disease severity and progression in patients with autosomal dominant polycystic kidney disease

 

Univariable

Multivariable

Stepwise backward

St. β

p-value

St. β

p-value

Female sex

−0.20

0.02

  

Age (yrs)

0.18

0.04

0.19

0.03

BMI (kg/m2)

−0.01

0.92

  

AHT use

−0.06

0.48

  

SBP (mmHg)

−0.04

0.70

  

DBP (mmHg)

−0.05

0.60

  

Sodium intake (mmol/24 h)

0.06

0.50

  

Protein intake (g/24 h)

0.19

0.04

0.20

0.03

Coffee use (cups/day)

0.20

0.04

  

PKD2 (ref)a

    

 PKD1 truncating

−0.10

0.53

  

 PKD1 non-truncating

−0.09

0.59

  
  1. Standardized beta’s and p-values were calculated using linear regression analysis. Dependent variable is the log transformed SST concentration, independent variables are sex, age, BMI, AHT, SBP, DBP, sodium intake, protein intake and coffee use
  2. Abbreviations are: BMI body mass index, AHT antihypertensive therapy, SBP, systolic blood pressure, DBP diastolic blood pressure, PKD polycystic kidney disease, St. β standardized beta
  3. aPKD mutation was used as dummy variable with PKD2 as reference group