Table 1 Demographic and Clinical Characteristics of Participants
Retrospective (n = 19) | Prospective (n = 15) | P value | |
|---|---|---|---|
Male, n (%) | 8 (42) | 10 (67) | 0.185 |
Black, n (%) | 11 (58) | 5 (33) | 0.185 |
Mean Age at Tx, yr. ± SD | 40 ± 12 | 38 ± 16 | 0.703 |
Mean Age at native FSGS Diagnosis, yr. ± SD | 29 ± 8 | 30 ± 17 | 0.859 |
Median Duration on Dialysis, yr. (IQR) | 2.5 (1.5, 8.0) | 3.8 (1.3, 6.0) | 0.888 |
Pre-Tx Urine, n (%) | 13 (68) | 6 (40) | 0.165 |
Mean Pre-Transplant Proteinuria, g/g ± SD | 9.43 ± 12 | 8.88 ± 7.32 | 0.673 |
Primary Pre-Tx Diagnosis, n (%) | |||
FSGS | 17 (89) | 15 (100) | 0.492 |
Other* | 2 (11) | ||
No. of Transplants, n (%) | |||
1 | 12 (63) | 8 (53) | 0.659 |
2 | 4 (21) | 5 (33) | |
3 | 3 (16) | 1 (7) | |
Living Donor, n (%) | 12 (63) | 11 (73) | 0.469 |
Related | 5 (26) | 3 (20) | |
Unrelated | 7 (37) | 8 (53) | |
ABO-Incompatible Tx, n (%) | 4 (21) | 1 (7) | 0.633 |
Median Time to Post-Tx FSGS, days (IQR) | 31 (5, 238) | 33 (5, 299) | 0.589 |
Mean Proteinuria at time of Post-Tx FSGS, g/g ± SD | 4.7 ± 3.6 | 3.2 ± 2.8 | 0.366 |
Mean Peak Proteinuria, g/g ± SD | 10.94 ± 11.61 | 4.6 ± 3.25 | 0.061 |
Median Serum Creatinine at time of Post-Tx FSGS, mg/dL (IQR) | 2.5 (1.7, 3.5) | 1.5 (1.3, 2.4) | 0.310 |
Median eGFR at time of Post-Txp FSGS, mg/dL (IQR) | 32 (14, 44) | 55 (29, 61) | 0.943 |
Median TPE (IQR) | 14 (10, 27) | 10 (10, 19) | 0.447 |