Table 2 Baseline characteristics of apparently healthy young men in northwest Nicaragua stratified by trajectories of a future decline in kidney function using gold standard measurements (CKDEPI Creat/Cyst eGFR) (n = 263)
Trajectories of the decline in kidney function | N | Age at baseline (Mean; SD) | Serum creatinine level at baseline‡ (Median; IQR) | eGFRScr at baseline‡ (Median; IQR) | eGFRScr-Scys at baseline† (Median; IQR) | Urinary NGAL level at baseline◊ (Median; IQR) | UACR ≥30 mg/dL at baseline◊ (n; %) | Outdoor work at baseline (n; %) |
|---|---|---|---|---|---|---|---|---|
Stable kidney function (−0.6 mL/min/1.73 m2/year) | 213 | 23.6 ± 3.89 | 0.76 (0.57–0.76) | 131 (124–140) | 118 (108–125) | 5.04 (4.7–5.4) | 10 (4.7) | 151 (70.9) |
Rapid decline in kidney function (− 18.2 mL/min/1.73 m2/year) | 25 | 23.3 ± 3.65 | 0.66 (0.47–0.76) | 132 (123–152) | 117 (103–124) | 5.20 (5.0–5.5) | 0 (0) | 24 (96.0) |
Renal dysfunction (− 3.8 mL/min/1.73 m2/year) | 25 | 25.4 ± 2.97 | 1.23 (1.14–1.52) | 80 (62–91) | 56 (49–68) | 5.7 (5.5–5.7) | 4 (16.0) | 19 (76.0) |
Total | 263 | 23.7 ± 3.82 | 0.76 (0.66–0.85) | 129 (121–139) | 116 (102–125) | 5.20 (4.9–5.7) | 14 (5.3) | 194 (73.8) |