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Fig. 3 | BMC Nephrology

Fig. 3

From: Gut derived-endotoxin contributes to inflammation in severe ischemic acute kidney injury

Fig. 3

Norfloxacin pretreatment reduces kidney TLR4 protein expression and renal proinflammatory mediators production. (a) Immunohistological staining of TLR4 in the kidney. (b) TLR4/GAPDH protein expression on densitometry. mRNA and protein levels of TNF-α (c, f), IL-6 (d, g) and MCP-1 (e, h) were measured in kidney hemogenates. Data are presented as mean ± SD. One-way ANOVA followed by Bonferroni multiple comparison test was used in all graphs (n = 5 per group). *P < 0.05, **P < 0.01, ***P < 0.001. (Original blots ‘BMC Additional file 1)

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