Skip to main content

Table 6 Detection of AKI using Cys C in patients with and without low T3 syndrome

From: Impact of thyroid function on cystatin C in detecting acute kidney injury: a prospective, observational study

 

Total AKIa

Established AKIb

Later-onset AKIc

AUC ROC

95%CI

Cut-off

P

AUC ROC

95%CI

Cut-off

P

AUC ROC

95%CI

Cut-off

P

Total

0.753 ± 0.015

0.724–0.782

1.03

< 0.001

0.797 ± 0.017

0.763–0.831

0.98

< 0.001

0.669 ± 0.022

0.626–0.712

1.03

< 0.001

Low T3 syndrome (n = 650)

0.762 ± 0.020

0.723–0.801

1.03

< 0.001

0.789 ± 0.023

0.744–0.833

1.04

< 0.001

0.669 ± 0.032

0.606–0.732

1.00

< 0.001

Without lowT3 syndrome (n = 689)

0.725 ± 0.023

0.681–0.769

0.78

< 0.001

0.784 ± 0.028

0.730–0.838

0.77

< 0.001

0.663 ± 0.030

0.604–0.722

0.59

< 0.001

  1. The cohort was stratified into two groups: 650 patients with low T3 syndrome, with FT3 < 3.80 pmol/L, FT4 and TSH within or lower than the normal range, and 689 patients without low T3 syndrome. aFor Total AKI, Z = 1.214, P = 0.225. bFor Established AKI, Z = 0.110, P = 0.912. cFor Later-onset AKI, Z = 0.138, P = 0.890. AKI acute kidney injury, AUC ROC area under the receiver operating characteristic curve, CI confidence interval, Cys C cystatin C, FT3 free triiodothyronine, FT4 free thyroxine, TSH thyroid-stimulating-hormone