The effects of add-on corticosteroids on renal outcomes in patients with biopsy proven HIV associated nephropathy: a single centre study from South Africa

Table 3 The change [Δ] in clinical and biochemical parameters at 24 months

Median change [Δ] in parameters at 24 months [IQR]	[ART + C]	[ART Alone]	P Value^a
Clinical parameters
Systolic BP mmHg [IQR]	10 [−25; 11]	6 [2; 18]	0.466
Diastolic BP mmHg [IQR]	−6 [−20;4]	1 [−5; 7]	0.177
Biochemical parameters
Change in eGFR (ml/min/1.73m²) [IQR]	25 [15;51]	9 [0;24]	0.008
Change in uPCR (gm/mmol) [IQR]	−0.13 [−0.25; −0.08]	−0.12 [−0.55; −0.06]	0.691
Change in Haemoglobin (gm/dL)[IQR]	3.4 [0.3; 4.7]	3.6 [2.1; 4.8]	0.480
Change in Albumin (gm/L)[IQR]	5 [2; 12]	6 [4;15]	0.445
Change in Cholesterol (mmol/l)[IQR]	0.2 [−0.10; 1.7]	0.3 [−1.5; 0.9]	0.577

ART + C Antiretrovirals + corticosteroids, ART Alone Antiretrovirals alone, BP Blood pressure, eGFR estimated glomerular filtration rate, uPCR protein creatinine ratio, a = Wilcoxon Rank-Sum test

ISSN: 1471-2369