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Table 5 Improvement in histological feature

From: The effects of add-on corticosteroids on renal outcomes in patients with biopsy proven HIV associated nephropathy: a single centre study from South Africa

  ART + C
N = 12
ART alone
N = 9
 
Histological feature Baseline Histology [n = 21] Repeat biopsy [n = 12] Repeat biopsies that improved (%) Baseline histology [n = 17] Repeat Histology
[n = 9]
Repeat biopsies that improved (%) P Valuea
Lymphocytic infiltration   50.0%   55.6% 1.000
 0 4.8% 0.0% 5.9% 22.2%
 1 8.6% 58.3% 41.2% 44.4%
 2 23.8% 33.3% 29.4% 33.3%
 3 28.6% 8.3% 11.8% 0.0%
 4 14.3% 0.0% 11.8% 0.0%
Plasma cell infiltration   75%   44.4% 0.203
 0 4.8% 8.3% 5.9% 11.1%
 1 28.6% 25.0% 29.4% 66.7%
 2 9.5% 41.7% 29.4% 11.1%
 3 19.0% 25.0% 5.9% 11.1%
 4 38.1% 0.0% 29.4% 0.0%
Interstitial fibrosis   75.0%   44.4% 0.203
 0 0.0% 0.0% 11.8% 33.3%
 1 14.3% 50.0% 35.3% 44.4%
 2 14.3% 41.7% 11.8% 22.2%
 3 23.8% 8.3% 29.4% 0.0%
 4 4.8% 0.0% 11.8% 0.0%
Microcysts   41.8%   22.2% 0.642
 0 23.8% 50.0% 41.2% 77.7%
 1 33.3% 50.0% 23.5% 11.1%
 2 33.3% 0.0% 23.5% 11.1%
 3 9.5% 0% 11.8% 0%
 4 0.0% 0% 0% 0%
  1. ART + C Antiretrovirals + corticosteroids, ART Alone Antiretrovirals alone, a = Fisher’s Exact Test to compare improvements in histology on repeat biopsy between groups