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Table 4 Associations of electrolytes and dialysis parameters with RCA rate from the beginning of each dialysis session to 8-h post-dialysis

From: Relationship between dialytic parameters and reviewer confirmed arrhythmias in hemodialysis patients in the monitoring in dialysis study

Parameter Crude IRR (95% CI) P Value Adjusted IRR (95% CI) P Value
Electrolyte Concentration
 Pre-dialysis potassium 1.26 (0.96, 1.65) 0.10 1.28 (0.97, 1.69) 0.08
 Intradialytic potassium change 0.78 (0.60, 1.01) 0.06 0.78 (0.60, 1.01) 0.06
 Pre-dialysis calcium 0.92 (0.65, 1.31) 0.65 0.80 (0.56, 1.15) 0.23
 Intra-dialytic calcium change 1.06 (0.83, 1.34) 0.65 1.16 (0.90, 1.49) 0.26
 Pre-dialysis magnesium 0.41 (0.21, 0.78) 0.01 0.49 (0.25, 0.94) 0.03
 Intradialytic magnesium change 1.29 (0.57, 2.94) 0.54 1.56 (0.64, 3.78) 0.33
 Pre-dialysis phosphorus 1.06 (0.89, 1.26) 0.53 1.00 (0.84, 1.19) 0.96
 Intradialytic phosphorus change 0.95 (0.80, 1.14) 0.58 1.02 (0.84, 1.23) 0.86
 Pre-dialysis bicarbonate 1.01 (0.95, 1.07) 0.78 0.97 (0.93, 1.03) 0.28
 Intradialytic bicarbonate change 0.98 (0.92, 1.05) 0.62 0.99 (0.93, 1.06) 0.80
 Sodium pre-dialysis 1.07 (0.99, 1.15) 0.08 1.04 (0.97, 1.11) 0.25
 Intradialytic sodium change 0.97 (0.92, 1.03) 0.34 0.98 (0.93, 1.04) 0.54
Dialysis Prescription Parameters
 Dialysate temperature ≥ 37 vs. 36–36.9 °C 3.87 (0.95, 15.78) 0.06 4.30 (0.97, 19.17) 0.06
 Dialysis potassium 3 vs. 2 mEq/L 1.23 (0.63, 2.61) 0.49 1.12 (0.59, 2.13) 0.73
Dialysate calcium
  < 2 vs. 2.5 mEq/L 0.11 (0.04, 0.31) < 0.001 0.13 (0.03, 0.57) 0.01
 2.0–2.4 vs. 2.5 mEq/L 0.11 (0.00, 7.30) 0.30 0.09 (0.00, 10.50) 0.32
  > 2.5 vs. 2.5 mEq/L 0.54 (0.36, 0.83) 0.004 0.52 (0.39, 0.70) < 0.001
Dialysate Sodium
  ≤ 135 vs. 140 mEq/L 2.31 (0.59, 9.01) 0.23 2.31 (0.60, 8.93) 0.23
 135–139 vs. 140 mEq/L 0.38 (0.12, 1.21) 0.10 0.40 (0.17, 0.95) 0.04
 Sodium modelling (vs. fixed sodium) 0.57 (0.21, 1.58) 0.28 0.77 (0.37, 1.59) 0.47
Dialysate bicarbonate
  ≤ 28 vs. 35 mEq/L 0.25 (0.04, 1.69) 0.15 0.39 (0.07, 2.34) 0.31
  > 28–34 vs. 35 mEq/L 0.43 (0.18, 1.06) 0.07 0.96 (0.30, 3.07) 0.95
  > 35 vs. 35 mEq/L 0.74 (0.36, 1.52) 0.41 0.51 (0.27, 0.97) 0.04
 Intradialytic weight change (per Kilogram) 1.16 (1.02, 1.31) 0.02 1.10 (0.99, 1.22) 0.08
 Nadir SBP 1.00 (0.99, 1.01) 0.93 0.99 (0.98, 1.00) 0.21
 Nadir DBP 1.01 (0.99, 1.02) 0.35 1.00 (0.98, 1.02) 0.98
  1. Crude and adjusted associations with RCA rate from the start of one dialysis to 8 h after post dialysis. Adjusted models include age, sex, race, vascular access type, and dialysis vintage. All sessions are included. Kg-kilogram. mL-milliliter. mEq/L-milliequivalent/liter. Pre- and intradialytic potassium, calcium, bicarbonate and sodium per 1 mEq/L increase in electrolyte. Pre and intradialytic magnesium and phosphorous per 1 mg/dL change