Table 2 Safety Lab values
Lab value, (unit) | Baseline, mean (+/-SD) | EOT, mean (+/-SD) | SVR12, mean (+/-SD) | p (one-way ANOVA) |
|---|---|---|---|---|
ALT (U/l) | 48.31 (31.71) | 20.56 (10.52) | 19.06 (7.88) | <0.0001 |
AST (U/l) | 42.06 (16.78) | 27.75 (12.37) | 23.0 (12.37) | <0.0001 |
AP (U/l) | 87.06 (40.25) | 79.69 (40.93) | 82.50 (46.18) | 0.89 |
GGT (U/l) | 146.13 (282.40) | 55.00 (115.15) | 53.94 (116.97) | 0.29 |
Bilirubin, total (mg/dl) | 0.48 (0.22) | 0.31 (0.16) | 0.47 (0.29) | 0.068 |
Albumin (g(l) | 42.97 (3.48) | 43.14 (3.48) | 42.67 (4.79) | 0.944 |
Hb (g/dl) | 12.9 (1.5) | 12.1 (1.35) | 12.57 (1.52) | 0.31 |
Ferritin (μg/l) | 253.38 (163.37) | 124.11 (64.37) | 127.33 (63) | 0.002 |
HbA1c (%) | 5.59 (0.93) | 5.33 (0.52) | 5.54 (0.95) | 0.65 |
TG (mg/dl) | 145.5 (85.58) | 147.13 (88.45) | 136.06 (91.02) | 0.93 |
HDL (mg/dl) | 53.69 (18.54) | 55.44 (15.22) | 55.81 (15.18) | 0.93 |
CRP (mg/l) | 2.44 (2.71) | 3.95 (5.82) | 3.04 (3.22) | 0.59 |
creatinine (mg/dl) | 1.41 (0.44) | 1.52 (0.50) | 1.54 (0.51) | 0.71 |
proteinuria (mg/g creatinine) | 605.63 (1240.54) | 374.94 (549.25) | 440.94 (689.55) | 0.75 |
HOMA2-IR | 89.22 (33.77) | 103.3 (36.46) | 113.54 (70.35) | 0,24 |
HOMA2-B | 128.01 (91.83) | 114.21 (63.68) | 111.55 (71.23) | 0,63 |