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Table 1 Clinical variables of the 120 hemodialysis patients with or without low handgrip strength

From: Angiotensin II receptor blockade is associated with preserved muscle strength in chronic hemodialysis patients

Characteristics

All Patients (n = 120)

Normal HGS (n = 42)

Low HGS (n = 78)

P

Age (years)

63.3 ± 13.2

55.0 ± 10.1

67.8 ± 12.5

<  0.001*

HD duration (months)

56.5 (23.7–123.8)

47.4 (21.2–118.7)

59.6 (24.1–125.3)

0.214

SBP (mmHg)

142.6 ± 27.1

142.6 ± 26.1

142.6 ± 27.8

0.990

DBP (mmHg)

77.5 ± 16.6

80.2 ± 16.2

76.0 ± 16.8

0.192

Height (cm)

160.1 ± 8.7

164.0 ± 9.8

158.0 ± 7.3

0.001*

Post-HD body weight (kg)

62.2 ± 14.6

66.8 ± 16.0

59.8 ± 13.3

0.018*

BMI (kg/m2)

24.1 ± 4.6

24.6 ± 4.5

23.9 ± 4.7

0.436

SMI (kg/m2)

10.5 (8.2–13.8)

12.0 (8.8–15.6)

9.9 (7.5–13.4)

0.012*

Handgrip strength (kg)

22.2 ± 9.7

31.1 ± 7.7

17.2 ± 6.6

< 0.001*

Subjective global assessment

13.5 (10.0–17.0)

11.0 (10.0–14.0)

14.0 (11.0–18.0)

0.002*

Hemoglobin (g/dl)

10.4 (9.7–11.1)

10.5 (9.6–11.2)

10.4 (9.9–11.0)

0.789

Albumin (mg/dL)

4.1 (3.9–4.4)

4.2 (4.0–4.7)

4.1 (3.9–4.3)

0.133

Glucose (mg/dL)

129.0 (106.3–166.8)

123.0 (100.0–143.5)

131.5 (110.0–174.0)

0.058

Blood urea nitrogen (mg/dL)

61.4 ± 14.2

64.0 ± 13.5

60.1 ± 14.4

0.150

Creatinine (mg/dL)

9.6 ± 2.0

10.6 ± 2.2

9.1 ± 1.8

<  0.001*

Phosphorus (mg/dL)

4.7 ± 1.3

4.9 ± 1.3

4.7 ± 1.3

0.492

Intact parathyroid hormone (pg/mL)

206.1 (61.2–449.4)

254.5 (107.2–499.2)

195.0 (55.4–440.7)

0.376

C-reactive protein (mg/dL)

0.3 (0.1–0.9)

0.3 (0.1–0.6)

0.3 (0.1–1.0)

0.389

Kt/V (Gotch)

1.34 ± 0.17

1.29 ± 0.17

1.36 ± 0.17

0.020*

URR

0.73 ± 0.04

0.72 ± 0.04

0.74 ± 0.04

0.017*

  1. Values for continuous variables are given as means ± standard deviation and were tested for significant differences by Student’s t-test; variables not normally distributed are shown as medians and interquartile range and were tested by Mann-Whitney U test
  2. HGS, handgrip strength; HD, hemodialysis; SBP, systolic blood pressure; DBP, diastolic blood pressure; SMI, skeletal muscle index; Kt/V, fractional clearance index for urea; URR, urea reduction ratio
  3. *P < 0.05 was considered statistically significant