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Table 2 Comparison of clinical and laboratory parameters according to acute kidney injury in expanded criteria donor or standard criteria donor kidney transplantation

From: Impact of acute kidney injury in expanded criteria deceased donors on post-transplant clinical outcomes: multicenter cohort study

Variables

SCD-KT

ECD-KT

Non-AKI-KT

AKI-KT

p for Trend

Non-AKI-KT

AKI-KT

p for Trend

Donors

n = 166

n = 112

 

n = 27

n = 81

 

 Age at KT (years)

38.3 ± 14.5

39.9 ± 11.8

0.329

61.0 ± 3.4

57.5 ± 5.4

< 0.001

 Gender (Male: Female)

107: 59

81: 31

0.192

16: 11

63: 18

0.079

 BMI (kg/m2)

21.9 ± 3.7

23.8 ± 3.8

< 0.001

23.9 ± 2.7

23.0 ± 2.7

0.156

 HTN, n (%)

23 (14.5)

13 (11.8)

0.588

15 (55.6)

35 (44.9)

0.377

 DM, n (%)

11 (6.8)

4 (3.6)

0.293

3 (11.1)

16 (20.5)

0.388

 Cause of donor death - CVA, n (%)

114 (68.7)

88 (78.6)

0.076

23 (85.2)

66 (81.5)

0.777

Recipients

n = 196

n = 154

 

n = 43

n = 116

 

 Age at KT (yr)

46.3 ± 9.5

47.1 ± 11.0

0.340

51.9 ± 9.3

50.8 ± 9.5

0.524

 Gender (Male: Female)

105: 91

86: 68

0.746

29: 14

71: 45

0.580

 BMI (kg/m2)

22.5 ± 3.3

22.5 ± 2.9

0.681

23.6 ± 3.2

23.3 ± 3.4

0.681

 HTN, n (%)

163 (83.2)

134 (87.0)

0.369

36 (83.7)

103 (88.8)

0.423

 DM, n (%)

26 (13.3)

29 (18.8)

0.183

11 (25.6)

32 (27.6)

0.844

 Dialysis before KT, n (%)

193 (98.5)

151 (98.1)

1.000

42 (97.7)

116 (100.0)

0.270

 Dialysis duration, years

7.8 ± 4.9

6.8 ± 4.3

0.321

5.9 ± 4.5

8.3 ± 15.0

0.305

 Previous KT, n (%)

21 (10.7)

20 (13.0)

0.616

2 (4.7)

8 (6.9)

0.730

 Cause of ESRD, n (%)

  

0.013

  

0.768

  Glomerulonephritis

107 (54.6)

58 (37.7)

 

15 (34.9)

38 (32.8)

 

  DM

20 (10.2)

25 (16.2)

 

9 (20.9)

27 (23.3)

 

  HTN

30 (15.3)

27 (17.5)

 

9 (20.9)

31 (26.7)

 

  Others

39 (19.9)

44 (28.6)

 

10 (23.3)

20 (17.2)

 

 Cold ischemic time (min)

243 ± 132

245 ± 131

0.927

235 ± 99

242 ± 115

0.716

 HLA mismatch number

3.6 ± 1.5

3.8 ± 1.2

0.241

3.6 ± 1.6

3.8 ± 1.4

0.442

 Induction, n (%)

  

0.001

  

0.239

  Basiliximab

169 (86.2)

111 (72.1)

 

34 (79.1)

80 (69.0)

 

  ATG

27 (13.8)

43 (27.9)

 

9 (20.9)

36 (31.0)

 

 Main immunosuppressant, n (%)

  Tacrolimus: Cyclosporine

175: 20

141: 13

0.769

40: 3

113: 3

0.345

 PRA > 50%

30 (20.8)

22 (16.3)

0.359

4 (10.5)

16 (14.8)

0.595

  1. Values are expressed as means ± SDs, n (%)
  2. SCD standard criteria donor, ECD expanded criteria donor, AKI acute kidney injury, KT kidney transplantation, BMI body mass index, HTN hypertension, DM diabetes mellitus, CVA cerebrovascular accident, ESRD end-stage renal disease, HLA human leukocyte antigen, ATG antithymocyte globulin, PRA panel reactive antibody