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Table 2 Cox regression analysis for incident cerebrovascular disease according to baseline variables among 88 hemodialysis patients

From: Serum klotho: a potential predictor of cerebrovascular disease in hemodialysis patients

 

Univariable

Multivariable

HR(95% CI)

P

HR(95% CI)

P

Age, years

1.086 (1.037–1.138)

0.001**

1.104 (1.038–1.174)

0.002**

Male, n (%)

1.667 (0.632–4.392)

0.302

  

Diabetes history, n (%)

2.489 (0.927–6.680)

0.070

  

Hypertension, n (%)

1.500 (0.437–5.148)

0.519

  

Tobacco smoking, n (%)

1.083 (0.297–3.951)

0.904

  

HD vintage (months)

1.027 (1.002–1.053)

0.033*

1.027 (0.996–1.058)

0.086

Klotho (pg/ml)

0.977 (0.965–0.990)

0.001**

0.975 (0.960–0.990)

0.001**

Hb (g/L)

1.006 (0.977–1.063)

0.679

  

Ca (mmol/L)

1.298 (0.217–7.772)

0.775

  

P (mmol/L)

0.707 (0.291–1.718)

0.444

  

PTH (pg/ml)

0.999 (0.997–1.000)

0.095

  

SF (ng/ml)

0.996 (0.909–1.091)

0.931

  

Serum iron (umol/L)

1.000 (0.998–1.001)

0.395

  

TIBC (umol/L)

0.997 (0.949–1.048)

0.913

  

Tch (mmol/L)

1.249 (0.794–1.964)

0.336

  

TG (mmol/L)

1.448 (0.900–2.330)

0.127

  

LDL-C (mmol/L)

1.421 (0.756–2.669)

0.275

  

HDL-C (mmol/L)

0.382 (0.073–2.004)

0.255

  

ALB (g/L)

0.899 (0.778–1.038)

0.145

  
  1. Hb hemoglobin, Ca calcium, P phosphate, PTH parathyroid hormone, SF serum ferritin, TIBC Total iron binding capacity, Tch total cholesterol, TG triglycerides, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, ALB albumin, HR hazard ratio, 95% CI 95% confidence interval
  2. *p < 0.05; **p < 0.01