Model
|
HR
|
95% CI
|
P
|
---|
IS (continuous variable)
|
Unadjusted
|
1.47
|
1.12–1.93
|
0.006
|
Model 1
|
1.48
|
1.11–1.96
|
0.007
|
Model 2
|
1.51
|
1.15–2.00
|
0.003
|
Model 3
|
1.47
|
1.11–1.97
|
0.008
|
Model 4
|
1.61
|
1.19–2.17
|
0.002
|
Model 5
|
1.74
|
1.27–2.39
|
0.001
|
IS (dichotomous variable)
|
Unadjusted
|
1.75
|
1.16–2.64
|
0.008
|
Model 1
|
1.75
|
1.18–2.70
|
0.006
|
Model 2
|
2.01
|
1.30–3.10
|
0.002
|
Model 3
|
2.00
|
1.28–3.14
|
0.002
|
Model 4
|
2.47
|
1.53–3.98
|
< 0.001
|
Model 5
|
2.92
|
1.76–4.86
|
< 0.001
|
- Variables of model 1 include age and gender
- Variables of model 2 include age, gender, non-renal APACHE II score, sepsis, RRT, and surgery
- Variables of model 3 include age, gender, non-renal APACHE II score, sepsis, RRT, surgery, serum albumin, creatinine, BUN and β2-microglobulin
- Variables of model 4 include age, gender, non-renal APACHE II score, sepsis, RRT, surgery, serum albumin, creatinine, BUN, β2-microglobulin, ALT, neutrophilic granulocyte and platelet counts
- Variables of model 5 include age, gender, non-renal APACHE II score, sepsis, RRT, surgery, serum albumin, creatinine, BUN, β2-microglobulin, ALT, neutrophilic granulocyte, platelet counts, and interaction terms (gender*platelet counts, surgery*serum albumin, surgery*creatinine and ALT*platelet counts)