Skip to main content

Table 3 Multivariate Cox proportional hazard model of mortality during 90-day follow-up in AKI patients (β2-microglobulin entered as a continuous or dichotomous variable)

From: Serum indoxyl sulfate is associated with mortality in hospital-acquired acute kidney injury: a prospective cohort study

Model HR 95% CI P
β2-microglobulin (continuous variable)
 Unadjusted 1.03 1.00–1.07 0.041
 Model 1 1.03 1.00–1.07 0.056
 Model 2 1.00 0.96–1.04 0.929
 Model 3 1.00 0.95–1.03 0.590
 Model 4 1.01 0.96–1.05 0.813
 Model 5 1.01 0.96–1.05 0.800
β2-microglobulin(dichotomous variable)
 Unadjusted 1.69 1.11–2.57 0.014
 Model 1 1.67 1.10–2.53 0.017
 Model 2 1.01 0.65–1.57 0.970
 Model 3 0.88 0.55–1.40 0.581
 Model 4 1.00 0.61–1.61 0.966
 Model 5 1.00 0.61–1.67 0.987
  1. Variables of model 1 include age and gender
  2. Variables of model 2 include age, gender, non-renal APACHE II score, sepsis, RRT, and surgery
  3. Variables of model 3 include age, gender, non-renal APACHE II score, sepsis, RRT, surgery, serum albumin, IS, creatinine and BUN
  4. Variables of model 4 include age, gender, non-renal APACHE II score, sepsis, RRT, surgery, serum albumin, IS, creatinine, BUN, ALT, neutrophilic granulocyte and platelet counts
  5. Variables of model 5 include age, gender, non-renal APACHE II score, sepsis, RRT, surgery, serum albumin, IS, BUN, creatinine, ALT, neutrophilic granulocyte, platelet counts and interaction terms (gender*platelet counts, surgery*serum albumin, surgery*creatinine, and ALT*platelet counts)