Skip to main content
Fig. 4 | BMC Nephrology

Fig. 4

From: DPP-4 inhibition enhanced renal tubular and myocardial GLP-1 receptor expression decreased in CKD with myocardial infarction

Fig. 4

Change in treatment outcomes in CKD and CKD with linagliptin-treated rats. Blood pressure (a), urine volume (b), blood urea nitrogen (c), serum creatinine (d), albumin (e), and creatinine clearance (f). Control, sham-operated; CKD 2, 4, and 8 weeks, 5/6 nephrectomized rats 2, 4, and 8 weeks post-treatment; Lina, linagliptin. Values are presented as the mean ± SD. *p < 0.05 vs. control; **p < 0.01 vs. control; p < 0.05 vs. CKD, 2 weeks; ††p < 0.01 vs. CKD, 2 weeks; p < 0.05 vs. CKD, 4 weeks; ‡‡p < 0.01 vs. CKD, 4 weeks; ¥p < 0.05 vs. CKD, 8 weeks; and ¥¥p < 0.01 vs. CKD, 8 weeks

Back to article page