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Fig. 7 | BMC Nephrology

Fig. 7

From: DPP-4 inhibition enhanced renal tubular and myocardial GLP-1 receptor expression decreased in CKD with myocardial infarction

Fig. 7

Expression of renal tubular GLP-1R. A Western blots showing GLP-1R protein levels in the renal cortex of control; CKD, 8 weeks; CKD, 8 weeks + Lina; CKD, 8 weeks + MI/R; and CKD, 8 weeks + MI/R + Lina rats. B Quantification of GLP-1R protein levels were standardized based on β-actin expression in the renal cortex. C GLP-1R immunoreactivity of the renal cortex. a, f, and k, control; b, g, and i, CKD, 8 weeks; c, h, and m, CKD, 8 weeks with linagliptin-treated; d, i, and n, CKD, 8 weeks and MI/R; e, j, and o, CKD, 8 weeks and MI/R with linagliptin-treated group. CKD, chronic kidney disease; MI/R, myocardial ischemia/reperfusion; Lina, linagliptin. Black lines, separated from adjacent bands. Values are presented as the mean ± SD. *p < 0.05 vs. control. a–e, magnification 100×; f–o, magnification 400 ×

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BMC Nephrology

ISSN: 1471-2369

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