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Table 3 Plasma metabolites significantly (p < 0.05) associated with baseline ht-TKV. Effect size represents the magnitude and direction (+/−) of association between a given metabolite and ht-TKV, estimated by linear regression, while controlling for the selected HALT covariates, age, sex, genotype, site of sample collection, and BMI

From: Plasma metabolites and lipids associate with kidney function and kidney volume in hypertensive ADPKD patients early in the disease course

Metabolite Effect Size (SD) p-value FDR q-value KEGG ID PubChem ID
pseudo uridine 0.2273 (0.082) 0.0061 0.3375 C02067 15,047
aminomalonate 0.1240 (0.047) 0.0094 0.3375 C00872 100,714
Taurine −0.0577 (0.024) 0.0151 0.3375 C00245 1123
Tyrosine −0.1984 (0.082) 0.0156 0.3375 C00082 6057
isothreonic acid 0.1333 (0.055) 0.0166 0.3375 C21649 151,152
glutamic acid −0.1111 (0.048) 0.0217 0.3677 C00025 33,032
indole-3-lactate 0.1544 (0.070) 0.0273 0.3965 C02043 92,904
myo-inositol 0.1080 (0.052) 0.0373 0.4075 C00137 892
2-hydroxybutanoic acid −0.0940 (0.045) 0.0384 0.4075 C05984 440,864
Beta-D-fucose 0.0913 (0.046) 0.0482 0.4075 C02095 439,650