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Table 2 Modifiable practices: target ranges, percent of patients outside recommended range and associated relative risk of mortality

From: Potential life-years gained over a 5-year period by correcting DOPPS-identified modifiable practices in haemodialysis: results from the European MONITOR-CKD5 study

Country Kt/V Phosphate Hb Inter-Dialytic Weight Gain Albumin Facility Catheter Use All 6 Factors
Target range % outside range RR if outside range Target
Range
% outside range RR if outside range Target Range % outside range RR if outside range Target Range % outside range RR if outside range Target Range % outside range RR if outside range Target Range % outside range RR if outside range % inside range
on all 6
% outside range
on ≥1
RR if
outside range on ≥1
US[2] ≥1.2 12.1% 1.16 ≤5.5 mg/dL 49.2% 1.11 ≥11 g/dL 27.2% 1.14 ≤5.7% 12.5% 1.22 ≥3.5 g/dL 20.5% 1.38 ≤7% 50.0% 1.23 8.7% 91.3% 1.33
Belgium
[13]
≥1.2 30.3% 1.13 ≤1.5 mmol/L 56.2% 1.11 ≥11 g/dL 33.6% 1.20     ≥4.0 g/dL 67.1% 1.46 ≤10% 91.1% 1.20    
Spain
[14]
≥1.2 22.7% 1.13 ≤1.5 mmol/L 63.5% 1.11 ≥11 g/dL 30.4% 1.20     ≥4.0 g/dL 71.4% 1.46 ≤10% 42.8% 1.20    
France
[15]
≥1.2 15.5% 1.13 ≤1.8 mmol/L 39.6% 1.14 ≥11 g/dL 40.5% 1.20     ≥4.0 g/dL 70.5% 1.46 ≤10% 33.4% 1.20    
Sweden
[16]
≥1.2 20.1% 1.13 ≤1.8 mmol/L 50.8% 1.14 ≥11 g/dL 23.8% 1.20     ≥3.5 g/dL 40.1% 1.48 ≤10% 88.2% 1.20    
MONITOR-CKD5 * ≥1.2 17.1% 1.13 ≤5.5 mg/dL 38.5% 1.14 ≥10 g/dL 14.0% 1.22 ≤5.7% 7.8% 1.22 ≥4.0 g/dL 56.8% 1.46 Pt-level: fistula (native or synthetic) vs. catheter 16.6% 1.32 15.5% 84.5% 1.33
Source of RR for MONITOR-CKD5 Four European replications: Jadoul et al. 2007 [Ref 13], Piera et al. 2007 [Ref 14], Canaud et al. 2008 [Ref 15], Wikström et al. 2010 [Ref 16] Two European replications: Canaud et al. 2008 [Ref 15], Wikström et al. 2010 [Ref 16] Locatelli et al. 2004 [Ref 20] Port et al. 2004 [Ref 2] Three European replications: Jadoul et al. 2007 [Ref 13], Piera et al. 2007 [Ref 14], Canaud et al. 2008 [Ref 15] Pisoni et al. 2009 [Ref 21] RR if outside range on ≥1 modifiable factor extrapolated from Port et al. 2004 [Ref. 1] Tables 1 and 2 where RR = (overall mortality / mortality rate of patients outside of range) / % of patients outside range − % of patients inside range; % of patients inside range on all 6 factors obtained through personal communication with Arbor Research 23Sep2016
  1. * Valid % reported
  2. Hb haemoglobin, RR relative risk