Table 2 Modifiable practices: target ranges, percent of patients outside recommended range and associated relative risk of mortality
Country | Kt/V | Phosphate | Hb | Inter-Dialytic Weight Gain | Albumin | Facility Catheter Use | All 6 Factors | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Target range | % outside range | RR if outside range | Target Range | % outside range | RR if outside range | Target Range | % outside range | RR if outside range | Target Range | % outside range | RR if outside range | Target Range | % outside range | RR if outside range | Target Range | % outside range | RR if outside range | % inside range on all 6 | % outside range on ≥1 | RR if outside range on ≥1 | |
US[2] | ≥1.2 | 12.1% | 1.16 | ≤5.5 mg/dL | 49.2% | 1.11 | ≥11 g/dL | 27.2% | 1.14 | ≤5.7% | 12.5% | 1.22 | ≥3.5 g/dL | 20.5% | 1.38 | ≤7% | 50.0% | 1.23 | 8.7% | 91.3% | 1.33 |
Belgium [13] | ≥1.2 | 30.3% | 1.13 | ≤1.5 mmol/L | 56.2% | 1.11 | ≥11 g/dL | 33.6% | 1.20 | ≥4.0 g/dL | 67.1% | 1.46 | ≤10% | 91.1% | 1.20 | ||||||
Spain [14] | ≥1.2 | 22.7% | 1.13 | ≤1.5 mmol/L | 63.5% | 1.11 | ≥11 g/dL | 30.4% | 1.20 | ≥4.0 g/dL | 71.4% | 1.46 | ≤10% | 42.8% | 1.20 | ||||||
France [15] | ≥1.2 | 15.5% | 1.13 | ≤1.8 mmol/L | 39.6% | 1.14 | ≥11 g/dL | 40.5% | 1.20 | ≥4.0 g/dL | 70.5% | 1.46 | ≤10% | 33.4% | 1.20 | ||||||
Sweden [16] | ≥1.2 | 20.1% | 1.13 | ≤1.8 mmol/L | 50.8% | 1.14 | ≥11 g/dL | 23.8% | 1.20 | ≥3.5 g/dL | 40.1% | 1.48 | ≤10% | 88.2% | 1.20 | ||||||
MONITOR-CKD5 * | ≥1.2 | 17.1% | 1.13 | ≤5.5 mg/dL | 38.5% | 1.14 | ≥10 g/dL | 14.0% | 1.22 | ≤5.7% | 7.8% | 1.22 | ≥4.0 g/dL | 56.8% | 1.46 | Pt-level: fistula (native or synthetic) vs. catheter | 16.6% | 1.32 | 15.5% | 84.5% | 1.33 |
Source of RR for MONITOR-CKD5 | Four European replications: Jadoul et al. 2007 [Ref 13], Piera et al. 2007 [Ref 14], Canaud et al. 2008 [Ref 15], Wikström et al. 2010 [Ref 16] | Two European replications: Canaud et al. 2008 [Ref 15], Wikström et al. 2010 [Ref 16] | Locatelli et al. 2004 [Ref 20] | Port et al. 2004 [Ref 2] | Three European replications: Jadoul et al. 2007 [Ref 13], Piera et al. 2007 [Ref 14], Canaud et al. 2008 [Ref 15] | Pisoni et al. 2009 [Ref 21] | RR if outside range on ≥1 modifiable factor extrapolated from Port et al. 2004 [Ref. 1] Tables 1 and 2 where RR = (overall mortality / mortality rate of patients outside of range) / % of patients outside range − % of patients inside range; % of patients inside range on all 6 factors obtained through personal communication with Arbor Research 23Sep2016 | ||||||||||||||